diff --git a/clang/lib/Headers/cpuid.h b/clang/lib/Headers/cpuid.h
--- a/clang/lib/Headers/cpuid.h
+++ b/clang/lib/Headers/cpuid.h
@@ -328,4 +328,14 @@
     return 1;
 }
 
+// In some configurations, __cpuidex is defined as a builtin (primarily
+// -fms-extensions) which will conflict with the __cpuidex definition below.
+#if !(__has_builtin(__cpuidex))
+static __inline void __cpuidex (int __cpu_info[4], int __leaf, int __subleaf)
+{
+  __cpuid_count(__leaf, __subleaf, __cpu_info[0], __cpu_info[1], __cpu_info[2],
+                __cpu_info[3]);
+}
+#endif
+
 #endif /* __CPUID_H */
diff --git a/clang/test/Headers/__cpuidex_conflict.c b/clang/test/Headers/__cpuidex_conflict.c
new file mode 100644
--- /dev/null
+++ b/clang/test/Headers/__cpuidex_conflict.c
@@ -0,0 +1,22 @@
+// Make sure that __cpuidex in cpuid.h doesn't conflict with the MS
+// extensions built in by ensuring compilation succeeds:
+// RUN: %clang_cc1 %s -ffreestanding -fms-extensions -fms-compatibility \
+// RUN:  -fms-compatibility-version=19.00 -triple x86_64-pc-windows-msvc -emit-llvm -o -
+// %clang_cc1 %s -ffreestanding -triple x86_64-w64-windows-gnu -fms-extensions -emit-llvm -o -
+// RUN: %clang_cc1 %s -ffreestanding -fopenmp -fopenmp-is-target-device -aux-triple x86_64-unknown-linux-gnu
+
+typedef __SIZE_TYPE__ size_t;
+
+// We declare __cpuidex here as where the buitlin should be exposed (MSVC), the
+// declaration is in <intrin.h>, but <intrin.h> is not available from all the
+// targets that are being tested here.
+void __cpuidex (int[4], int, int);
+
+#include <cpuid.h>
+
+int cpuid_info[4];
+
+void test_cpuidex(unsigned level, unsigned count) {
+  __cpuidex(cpuid_info, level, count);
+}
+
diff --git a/clang/test/Headers/cpuid.c b/clang/test/Headers/cpuid.c
--- a/clang/test/Headers/cpuid.c
+++ b/clang/test/Headers/cpuid.c
@@ -6,14 +6,19 @@
 
 // CHECK-64: {{.*}} call { i32, i32, i32, i32 } asm "  xchgq  %rbx,${1:q}\0A cpuid\0A xchgq %rbx,${1:q}", "={ax},=r,={cx},={dx},0,~{dirflag},~{fpsr},~{flags}"(i32 %{{[a-z0-9]+}})
 // CHECK-64: {{.*}} call { i32, i32, i32, i32 } asm "  xchgq  %rbx,${1:q}\0A  cpuid\0A  xchgq  %rbx,${1:q}", "={ax},=r,={cx},={dx},0,2,~{dirflag},~{fpsr},~{flags}"(i32 %{{[a-z0-9]+}}, i32 %{{[a-z0-9]+}})
+// CHECK-64: {{.*}} call { i32, i32, i32, i32 } asm "  xchgq  %rbx,${1:q}\0A  cpuid\0A  xchgq  %rbx,${1:q}", "={ax},=r,={cx},={dx},0,2,~{dirflag},~{fpsr},~{flags}"(i32 %{{[a-z0-9]+}}, i32 %{{[a-z0-9]+}})
 
 // CHECK-32: {{.*}} call { i32, i32, i32, i32 } asm "cpuid", "={ax},={bx},={cx},={dx},0,~{dirflag},~{fpsr},~{flags}"(i32 %{{[a-z0-9]+}})
 // CHECK-32: {{.*}} call { i32, i32, i32, i32 } asm "cpuid", "={ax},={bx},={cx},={dx},0,2,~{dirflag},~{fpsr},~{flags}"(i32 %{{[a-z0-9]+}}, i32 %{{[a-z0-9]+}})
+// CHECK-32: {{.*}} call { i32, i32, i32, i32 } asm "cpuid", "={ax},={bx},={cx},={dx},0,2,~{dirflag},~{fpsr},~{flags}"(i32 %{{[a-z0-9]+}}, i32 %{{[a-z0-9]+}})
 
 unsigned eax0, ebx0, ecx0, edx0;
 unsigned eax1, ebx1, ecx1, edx1;
 
+int cpuid_info[4];
+
 void test_cpuid(unsigned level, unsigned count) {
   __cpuid(level, eax1, ebx1, ecx1, edx1);
   __cpuid_count(level, count, eax0, ebx0, ecx0, edx0);
+  __cpuidex(cpuid_info, level, count);
 }