diff --git a/llvm/include/llvm/CodeGen/GlobalISel/LegalizationArtifactCombiner.h b/llvm/include/llvm/CodeGen/GlobalISel/LegalizationArtifactCombiner.h
--- a/llvm/include/llvm/CodeGen/GlobalISel/LegalizationArtifactCombiner.h
+++ b/llvm/include/llvm/CodeGen/GlobalISel/LegalizationArtifactCombiner.h
@@ -325,6 +325,21 @@
       return true;
     }
 
+    // trunc(sext x) -> x
+    Register SextSrc;
+    if (mi_match(SrcReg, MRI, m_GSExt(m_Reg(SextSrc)))) {
+      LLT DstTy = MRI.getType(DstReg);
+      LLT SextSrcTy = MRI.getType(SextSrc);
+      if (DstTy == SextSrcTy) {
+        LLVM_DEBUG(dbgs() << ".. Combine MI: " << MI;);
+
+        replaceRegOrBuildCopy(DstReg, SextSrc, MRI, Builder, UpdatedDefs, Observer);
+        UpdatedDefs.push_back(DstReg);
+        markInstAndDefDead(MI, *MRI.getVRegDef(SrcReg), DeadInsts);
+        return true;
+      }
+    }
+
     return false;
   }
 
diff --git a/llvm/test/CodeGen/AMDGPU/GlobalISel/artifact-combiner-trunc.mir b/llvm/test/CodeGen/AMDGPU/GlobalISel/artifact-combiner-trunc.mir
--- a/llvm/test/CodeGen/AMDGPU/GlobalISel/artifact-combiner-trunc.mir
+++ b/llvm/test/CodeGen/AMDGPU/GlobalISel/artifact-combiner-trunc.mir
@@ -145,3 +145,18 @@
     %2:_(s32) = G_TRUNC %1
     $vgpr0 = COPY %2
 ...
+
+---
+name: trunc_sext
+
+body: |
+  bb.0:
+    ; Test that trunc(sext) is replaced with sext source.
+    ; CHECK-LABEL: name: trunc_sext
+    ; CHECK: [[DEF:%[0-9]+]]:_(s32) = G_IMPLICIT_DEF
+    ; CHECK-NEXT: $vgpr0 = COPY [[DEF]](s32)
+    %0:_(s32) = G_IMPLICIT_DEF
+    %1:_(s64) = G_SEXT %0
+    %2:_(s32) = G_TRUNC %1
+    $vgpr0 = COPY %2
+...