Index: clang/lib/Frontend/InitPreprocessor.cpp
===================================================================
--- clang/lib/Frontend/InitPreprocessor.cpp
+++ clang/lib/Frontend/InitPreprocessor.cpp
@@ -585,6 +585,11 @@
     Builder.defineMacro("__HIP_MEMORY_SCOPE_WORKGROUP", "3");
     Builder.defineMacro("__HIP_MEMORY_SCOPE_AGENT", "4");
     Builder.defineMacro("__HIP_MEMORY_SCOPE_SYSTEM", "5");
+    if (LangOpts.HIPStdPar) {
+      Builder.defineMacro("__HIPSTDPAR__");
+      if (!LangOpts.CUDAIsDevice)
+        Builder.defineMacro("__HIPSTDPAR_INTERPOSE_ALLOC__");
+    }
     if (LangOpts.CUDAIsDevice) {
       Builder.defineMacro("__HIP_DEVICE_COMPILE__");
       if (!TI.hasHIPImageSupport()) {
Index: clang/test/Preprocessor/predefined-macros.c
===================================================================
--- clang/test/Preprocessor/predefined-macros.c
+++ clang/test/Preprocessor/predefined-macros.c
@@ -290,3 +290,19 @@
 // RUN:   -fcuda-is-device -fgpu-default-stream=per-thread \
 // RUN:   | FileCheck -match-full-lines %s --check-prefix=CHECK-PTH
 // CHECK-PTH: #define HIP_API_PER_THREAD_DEFAULT_STREAM 1
+
+// RUN: %clang_cc1 %s -E -dM -o - -x hip -hipstdpar -triple x86_64-unknown-linux-gnu \
+// RUN:   | FileCheck -match-full-lines %s --check-prefix=CHECK-HIPSTDPAR
+// CHECK-HIPSTDPAR: #define __HIPSTDPAR__ 1
+
+// RUN: %clang_cc1 %s -E -dM -o - -x hip -hipstdpar -hipstdpar-interpose-alloc \
+// RUN:  -triple x86_64-unknown-linux-gnu | FileCheck -match-full-lines %s \
+// RUN:  --check-prefix=CHECK-HIPSTDPAR-INTERPOSE
+// CHECK-HIPSTDPAR-INTERPOSE: #define __HIPSTDPAR_INTERPOSE_ALLOC__ 1
+// CHECK-HIPSTDPAR-INTERPOSE: #define __HIPSTDPAR__ 1
+
+// RUN: %clang_cc1 %s -E -dM -o - -x hip -hipstdpar -hipstdpar-interpose-alloc \
+// RUN:  -triple amdgcn-amd-amdhsa -fcuda-is-device | FileCheck -match-full-lines \
+// RUN:  %s --check-prefix=CHECK-HIPSTDPAR-INTERPOSE-DEV-NEG
+// CHECK-HIPSTDPAR-INTERPOSE-DEV-NEG: #define __HIPSTDPAR__ 1
+// CHECK-HIPSTDPAR-INTERPOSE-DEV-NEG-NOT: #define __HIPSTDPAR_INTERPOSE_ALLOC__ 1
\ No newline at end of file