diff --git a/clang/lib/Driver/ToolChains/Serenity.cpp b/clang/lib/Driver/ToolChains/Serenity.cpp
--- a/clang/lib/Driver/ToolChains/Serenity.cpp
+++ b/clang/lib/Driver/ToolChains/Serenity.cpp
@@ -178,6 +178,8 @@
     CmdArgs.push_back(Args.MakeArgString(TC.GetFilePath("crtn.o")));
   }
 
+  TC.addProfileRTLibs(Args, CmdArgs);
+
   const char *Exec = Args.MakeArgString(TC.GetLinkerPath());
   C.addCommand(std::make_unique<Command>(JA, *this,
                                          ResponseFileSupport::AtFileCurCP(),
diff --git a/clang/test/Driver/instrprof-ld.c b/clang/test/Driver/instrprof-ld.c
--- a/clang/test/Driver/instrprof-ld.c
+++ b/clang/test/Driver/instrprof-ld.c
@@ -54,6 +54,15 @@
 // CHECK-OPENBSD-X86-64: "{{(.*[^-.0-9A-Z_a-z])?}}ld{{(.exe)?}}"
 // CHECK-OPENBSD-X86-64: "{{.*}}/Inputs/resource_dir{{/|\\\\}}lib{{/|\\\\}}openbsd{{/|\\\\}}libclang_rt.profile-x86_64.a"
 
+// RUN: %clang -### %s 2>&1 \
+// RUN:     --target=x86_64-pc-serenity -fprofile-instr-generate -fuse-ld=ld \
+// RUN:     -resource-dir=%S/Inputs/resource_dir \
+// RUN:     --sysroot=%S/Inputs/serenity_x86_64_tree \
+// RUN:   | FileCheck --check-prefix=CHECK-SERENITY-X86-64 %s
+
+// CHECK-SERENITY-X86-64: "{{(.*[^-.0-9A-Z_a-z])?}}ld.lld{{(.exe)?}}"
+// CHECK-SERENITY-X86-64: "{{.*}}/Inputs/resource_dir{{/|\\\\}}lib{{/|\\\\}}serenity{{/|\\\\}}libclang_rt.profile-x86_64.a"
+
 // RUN: %clang -### %s 2>&1 \
 // RUN:     -shared \
 // RUN:     --target=i386-unknown-linux -fprofile-instr-generate -fuse-ld=ld \
@@ -104,6 +113,17 @@
 // CHECK-OPENBSD-X86-64-SHARED: "{{(.*[^-.0-9A-Z_a-z])?}}ld{{(.exe)?}}"
 // CHECK-OPENBSD-X86-64-SHARED: "{{.*}}/Inputs/resource_dir{{/|\\\\}}lib{{/|\\\\}}openbsd{{/|\\\\}}libclang_rt.profile-x86_64.a"
 
+// RUN: %clang -### %s 2>&1 \
+// RUN:     -shared \
+// RUN:     --target=x86_64-pc-serenity -fprofile-instr-generate -fuse-ld=ld \
+// RUN:     -resource-dir=%S/Inputs/resource_dir \
+// RUN:     --sysroot=%S/Inputs/serenity_x86_64_tree \
+// RUN:   | FileCheck --check-prefix=CHECK-SERENITY-X86-64-SHARED %s
+
+// CHECK-SERENITY-X86-64-SHARED: "{{(.*[^-.0-9A-Z_a-z])?}}ld.lld{{(.exe)?}}"
+// CHECK-SERENITY-X86-64-SHARED: "{{.*}}/Inputs/resource_dir{{/|\\\\}}lib{{/|\\\\}}serenity{{/|\\\\}}libclang_rt.profile-x86_64.a"
+
+
 // RUN: %clang -### %s 2>&1 \
 // RUN:     --target=x86_64-apple-darwin14 -fprofile-instr-generate -fuse-ld=ld \
 // RUN:     -resource-dir=%S/Inputs/resource_dir \
diff --git a/compiler-rt/cmake/config-ix.cmake b/compiler-rt/cmake/config-ix.cmake
--- a/compiler-rt/cmake/config-ix.cmake
+++ b/compiler-rt/cmake/config-ix.cmake
@@ -789,7 +789,7 @@
 endif()
 
 if (PROFILE_SUPPORTED_ARCH AND NOT LLVM_USE_SANITIZER AND
-    OS_NAME MATCHES "Darwin|Linux|FreeBSD|Windows|Android|Fuchsia|SunOS|NetBSD|AIX")
+    OS_NAME MATCHES "Darwin|Linux|FreeBSD|Windows|Android|Fuchsia|SunOS|NetBSD|AIX|SerenityOS")
   set(COMPILER_RT_HAS_PROFILE TRUE)
 else()
   set(COMPILER_RT_HAS_PROFILE FALSE)
diff --git a/compiler-rt/lib/profile/InstrProfilingPlatformLinux.c b/compiler-rt/lib/profile/InstrProfilingPlatformLinux.c
--- a/compiler-rt/lib/profile/InstrProfilingPlatformLinux.c
+++ b/compiler-rt/lib/profile/InstrProfilingPlatformLinux.c
@@ -8,7 +8,7 @@
 
 #if defined(__linux__) || defined(__FreeBSD__) || defined(__Fuchsia__) || \
     (defined(__sun__) && defined(__svr4__)) || defined(__NetBSD__) || \
-    defined(_AIX)
+    defined(_AIX) || defined(__serenity__)
 
 #if !defined(_AIX)
 #include <elf.h>
diff --git a/compiler-rt/lib/profile/InstrProfilingPlatformOther.c b/compiler-rt/lib/profile/InstrProfilingPlatformOther.c
--- a/compiler-rt/lib/profile/InstrProfilingPlatformOther.c
+++ b/compiler-rt/lib/profile/InstrProfilingPlatformOther.c
@@ -8,7 +8,8 @@
 
 #if !defined(__APPLE__) && !defined(__linux__) && !defined(__FreeBSD__) &&     \
     !defined(__Fuchsia__) && !(defined(__sun__) && defined(__svr4__)) &&       \
-    !defined(__NetBSD__) && !defined(_WIN32) && !defined(_AIX)
+    !defined(__NetBSD__) && !defined(_WIN32) && !defined(_AIX) &&              \
+    !defined(__serenity__)
 
 #include <stdlib.h>
 #include <stdio.h>
diff --git a/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp b/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
--- a/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
+++ b/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
@@ -1042,7 +1042,8 @@
     return false;
   // Use linker script magic to get data/cnts/name start/end.
   if (TT.isOSAIX() || TT.isOSLinux() || TT.isOSFreeBSD() || TT.isOSNetBSD() ||
-      TT.isOSSolaris() || TT.isOSFuchsia() || TT.isPS() || TT.isOSWindows())
+      TT.isOSSolaris() || TT.isOSFuchsia() || TT.isPS() || TT.isOSWindows() ||
+      TT.isOSSerenity())
     return false;
 
   return true;