diff --git a/llvm/lib/Target/LoongArch/LoongArchInstrInfo.td b/llvm/lib/Target/LoongArch/LoongArchInstrInfo.td
--- a/llvm/lib/Target/LoongArch/LoongArchInstrInfo.td
+++ b/llvm/lib/Target/LoongArch/LoongArchInstrInfo.td
@@ -114,20 +114,20 @@
 def loongarch_syscall : SDNode<"LoongArchISD::SYSCALL", SDT_LoongArchVI,
                                 [SDNPHasChain, SDNPSideEffect]>;
 def loongarch_csrrd : SDNode<"LoongArchISD::CSRRD", SDT_LoongArchCsrrd,
-                              [SDNPHasChain]>;
+                              [SDNPHasChain, SDNPSideEffect]>;
 def loongarch_csrwr : SDNode<"LoongArchISD::CSRWR", SDT_LoongArchCsrwr,
                               [SDNPHasChain, SDNPSideEffect]>;
 def loongarch_csrxchg : SDNode<"LoongArchISD::CSRXCHG",
                                 SDT_LoongArchCsrxchg,
                                 [SDNPHasChain, SDNPSideEffect]>;
 def loongarch_iocsrrd_b : SDNode<"LoongArchISD::IOCSRRD_B", SDTUnaryOp,
-                                  [SDNPHasChain]>;
+                                  [SDNPHasChain, SDNPSideEffect]>;
 def loongarch_iocsrrd_h : SDNode<"LoongArchISD::IOCSRRD_H", SDTUnaryOp,
-                                  [SDNPHasChain]>;
+                                  [SDNPHasChain, SDNPSideEffect]>;
 def loongarch_iocsrrd_w : SDNode<"LoongArchISD::IOCSRRD_W", SDTUnaryOp,
-                                  [SDNPHasChain]>;
+                                  [SDNPHasChain, SDNPSideEffect]>;
 def loongarch_iocsrrd_d : SDNode<"LoongArchISD::IOCSRRD_D", SDTUnaryOp,
-                                  [SDNPHasChain]>;
+                                  [SDNPHasChain, SDNPSideEffect]>;
 def loongarch_iocsrwr_b : SDNode<"LoongArchISD::IOCSRWR_B",
                                   SDT_LoongArchIocsrwr,
                                   [SDNPHasChain, SDNPSideEffect]>;
diff --git a/llvm/test/CodeGen/LoongArch/intrinsic-csr-side-effects.ll b/llvm/test/CodeGen/LoongArch/intrinsic-csr-side-effects.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/LoongArch/intrinsic-csr-side-effects.ll
@@ -0,0 +1,47 @@
+; NOTE: Assertions have been autogenerated by utils/update_llc_test_checks.py
+; RUN: llc --mtriple=loongarch32 < %s | FileCheck %s
+; RUN: llc --mtriple=loongarch64 < %s | FileCheck %s
+
+declare i32 @llvm.loongarch.csrrd.w(i32 immarg) nounwind
+declare i32 @llvm.loongarch.csrwr.w(i32, i32 immarg) nounwind
+declare void @bug()
+
+define dso_local void @foo(i32 noundef signext %flag) nounwind {
+; CHECK-LABEL: foo:
+; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    beqz $a0, .LBB0_2
+; CHECK-NEXT:  # %bb.1: # %if.then
+; CHECK-NEXT:    csrrd $a0, 2
+; CHECK-NEXT:    ori $a0, $a0, 1
+; CHECK-NEXT:    csrwr $a0, 2
+; CHECK-NEXT:  .LBB0_2: # %if.end
+; CHECK-NEXT:    csrrd $a0, 2
+; CHECK-NEXT:    andi $a0, $a0, 1
+; CHECK-NEXT:    bnez $a0, .LBB0_4
+; CHECK-NEXT:  # %bb.3: # %if.then2
+; CHECK-NEXT:    b %plt(bug)
+; CHECK-NEXT:  .LBB0_4: # %if.end3
+; CHECK-NEXT:    ret
+entry:
+  %tobool.not = icmp eq i32 %flag, 0
+  br i1 %tobool.not, label %if.end, label %if.then
+
+if.then:                                          ; preds = %entry
+  %0 = tail call i32 @llvm.loongarch.csrrd.w(i32 2)
+  %or = or i32 %0, 1
+  %1 = tail call i32 @llvm.loongarch.csrwr.w(i32 %or, i32 2)
+  br label %if.end
+
+if.end:                                           ; preds = %if.then, %entry
+  %2 = tail call i32 @llvm.loongarch.csrrd.w(i32 2)
+  %and = and i32 %2, 1
+  %tobool1.not = icmp eq i32 %and, 0
+  br i1 %tobool1.not, label %if.then2, label %if.end3
+
+if.then2:                                         ; preds = %if.end
+  tail call void @bug()
+  br label %if.end3
+
+if.end3:                                          ; preds = %if.then2, %if.end
+  ret void
+}
diff --git a/llvm/test/CodeGen/LoongArch/intrinsic-iocsr-side-effects.ll b/llvm/test/CodeGen/LoongArch/intrinsic-iocsr-side-effects.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/LoongArch/intrinsic-iocsr-side-effects.ll
@@ -0,0 +1,180 @@
+; NOTE: Assertions have been autogenerated by utils/update_llc_test_checks.py
+; RUN: llc --mtriple=loongarch64 < %s | FileCheck %s
+
+declare i32 @llvm.loongarch.iocsrrd.b(i32) nounwind
+declare void @llvm.loongarch.iocsrwr.b(i32, i32) nounwind
+declare i32 @llvm.loongarch.iocsrrd.h(i32) nounwind
+declare void @llvm.loongarch.iocsrwr.h(i32, i32) nounwind
+declare i32 @llvm.loongarch.iocsrrd.w(i32) nounwind
+declare void @llvm.loongarch.iocsrwr.w(i32, i32) nounwind
+declare i64 @llvm.loongarch.iocsrrd.d(i32) nounwind
+declare void @llvm.loongarch.iocsrwr.d(i64, i32) nounwind
+declare void @bug()
+
+define dso_local void @test_b(i32 noundef signext %flag) nounwind {
+; CHECK-LABEL: test_b:
+; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    beqz $a0, .LBB0_2
+; CHECK-NEXT:  # %bb.1: # %if.then
+; CHECK-NEXT:    ori $a0, $zero, 2
+; CHECK-NEXT:    iocsrrd.b $a1, $a0
+; CHECK-NEXT:    ori $a1, $a1, 1
+; CHECK-NEXT:    iocsrwr.b $a1, $a0
+; CHECK-NEXT:  .LBB0_2: # %if.end
+; CHECK-NEXT:    ori $a0, $zero, 2
+; CHECK-NEXT:    iocsrrd.b $a0, $a0
+; CHECK-NEXT:    andi $a0, $a0, 1
+; CHECK-NEXT:    bnez $a0, .LBB0_4
+; CHECK-NEXT:  # %bb.3: # %if.then2
+; CHECK-NEXT:    b %plt(bug)
+; CHECK-NEXT:  .LBB0_4: # %if.end3
+; CHECK-NEXT:    ret
+entry:
+  %tobool.not = icmp eq i32 %flag, 0
+  br i1 %tobool.not, label %if.end, label %if.then
+
+if.then:                                          ; preds = %entry
+  %0 = tail call i32 @llvm.loongarch.iocsrrd.b(i32 2)
+  %or = or i32 %0, 1
+  tail call void @llvm.loongarch.iocsrwr.b(i32 %or, i32 2)
+  br label %if.end
+
+if.end:                                           ; preds = %if.then, %entry
+  %1 = tail call i32 @llvm.loongarch.iocsrrd.b(i32 2)
+  %and = and i32 %1, 1
+  %tobool1.not = icmp eq i32 %and, 0
+  br i1 %tobool1.not, label %if.then2, label %if.end3
+
+if.then2:                                         ; preds = %if.end
+  tail call void @bug()
+  br label %if.end3
+
+if.end3:                                          ; preds = %if.then2, %if.end
+  ret void
+}
+
+define dso_local void @test_h(i32 noundef signext %flag) nounwind {
+; CHECK-LABEL: test_h:
+; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    beqz $a0, .LBB1_2
+; CHECK-NEXT:  # %bb.1: # %if.then
+; CHECK-NEXT:    ori $a0, $zero, 2
+; CHECK-NEXT:    iocsrrd.h $a1, $a0
+; CHECK-NEXT:    ori $a1, $a1, 1
+; CHECK-NEXT:    iocsrwr.h $a1, $a0
+; CHECK-NEXT:  .LBB1_2: # %if.end
+; CHECK-NEXT:    ori $a0, $zero, 2
+; CHECK-NEXT:    iocsrrd.h $a0, $a0
+; CHECK-NEXT:    andi $a0, $a0, 1
+; CHECK-NEXT:    bnez $a0, .LBB1_4
+; CHECK-NEXT:  # %bb.3: # %if.then2
+; CHECK-NEXT:    b %plt(bug)
+; CHECK-NEXT:  .LBB1_4: # %if.end3
+; CHECK-NEXT:    ret
+entry:
+  %tobool.not = icmp eq i32 %flag, 0
+  br i1 %tobool.not, label %if.end, label %if.then
+
+if.then:                                          ; preds = %entry
+  %0 = tail call i32 @llvm.loongarch.iocsrrd.h(i32 2)
+  %or = or i32 %0, 1
+  tail call void @llvm.loongarch.iocsrwr.h(i32 %or, i32 2)
+  br label %if.end
+
+if.end:                                           ; preds = %if.then, %entry
+  %1 = tail call i32 @llvm.loongarch.iocsrrd.h(i32 2)
+  %and = and i32 %1, 1
+  %tobool1.not = icmp eq i32 %and, 0
+  br i1 %tobool1.not, label %if.then2, label %if.end3
+
+if.then2:                                         ; preds = %if.end
+  tail call void @bug()
+  br label %if.end3
+
+if.end3:                                          ; preds = %if.then2, %if.end
+  ret void
+}
+
+define dso_local void @test_w(i32 noundef signext %flag) nounwind {
+; CHECK-LABEL: test_w:
+; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    beqz $a0, .LBB2_2
+; CHECK-NEXT:  # %bb.1: # %if.then
+; CHECK-NEXT:    ori $a0, $zero, 2
+; CHECK-NEXT:    iocsrrd.w $a1, $a0
+; CHECK-NEXT:    ori $a1, $a1, 1
+; CHECK-NEXT:    iocsrwr.w $a1, $a0
+; CHECK-NEXT:  .LBB2_2: # %if.end
+; CHECK-NEXT:    ori $a0, $zero, 2
+; CHECK-NEXT:    iocsrrd.w $a0, $a0
+; CHECK-NEXT:    andi $a0, $a0, 1
+; CHECK-NEXT:    bnez $a0, .LBB2_4
+; CHECK-NEXT:  # %bb.3: # %if.then2
+; CHECK-NEXT:    b %plt(bug)
+; CHECK-NEXT:  .LBB2_4: # %if.end3
+; CHECK-NEXT:    ret
+entry:
+  %tobool.not = icmp eq i32 %flag, 0
+  br i1 %tobool.not, label %if.end, label %if.then
+
+if.then:                                          ; preds = %entry
+  %0 = tail call i32 @llvm.loongarch.iocsrrd.w(i32 2)
+  %or = or i32 %0, 1
+  tail call void @llvm.loongarch.iocsrwr.w(i32 %or, i32 2)
+  br label %if.end
+
+if.end:                                           ; preds = %if.then, %entry
+  %1 = tail call i32 @llvm.loongarch.iocsrrd.w(i32 2)
+  %and = and i32 %1, 1
+  %tobool1.not = icmp eq i32 %and, 0
+  br i1 %tobool1.not, label %if.then2, label %if.end3
+
+if.then2:                                         ; preds = %if.end
+  tail call void @bug()
+  br label %if.end3
+
+if.end3:                                          ; preds = %if.then2, %if.end
+  ret void
+}
+
+define dso_local void @test_d(i32 noundef signext %flag) nounwind {
+; CHECK-LABEL: test_d:
+; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    beqz $a0, .LBB3_2
+; CHECK-NEXT:  # %bb.1: # %if.then
+; CHECK-NEXT:    ori $a0, $zero, 2
+; CHECK-NEXT:    iocsrrd.d $a1, $a0
+; CHECK-NEXT:    ori $a1, $a1, 1
+; CHECK-NEXT:    iocsrwr.d $a1, $a0
+; CHECK-NEXT:  .LBB3_2: # %if.end
+; CHECK-NEXT:    ori $a0, $zero, 2
+; CHECK-NEXT:    iocsrrd.d $a0, $a0
+; CHECK-NEXT:    andi $a0, $a0, 1
+; CHECK-NEXT:    bnez $a0, .LBB3_4
+; CHECK-NEXT:  # %bb.3: # %if.then2
+; CHECK-NEXT:    b %plt(bug)
+; CHECK-NEXT:  .LBB3_4: # %if.end3
+; CHECK-NEXT:    ret
+entry:
+  %tobool.not = icmp eq i32 %flag, 0
+  br i1 %tobool.not, label %if.end, label %if.then
+
+if.then:                                          ; preds = %entry
+  %0 = tail call i64 @llvm.loongarch.iocsrrd.d(i32 2)
+  %or = or i64 %0, 1
+  tail call void @llvm.loongarch.iocsrwr.d(i64 %or, i32 2)
+  br label %if.end
+
+if.end:                                           ; preds = %if.then, %entry
+  %1 = tail call i64 @llvm.loongarch.iocsrrd.d(i32 2)
+  %and = and i64 %1, 1
+  %tobool1.not = icmp eq i64 %and, 0
+  br i1 %tobool1.not, label %if.then2, label %if.end3
+
+if.then2:                                         ; preds = %if.end
+  tail call void @bug()
+  br label %if.end3
+
+if.end3:                                          ; preds = %if.then2, %if.end
+  ret void
+}
diff --git a/llvm/test/CodeGen/LoongArch/intrinsic-la64.ll b/llvm/test/CodeGen/LoongArch/intrinsic-la64.ll
--- a/llvm/test/CodeGen/LoongArch/intrinsic-la64.ll
+++ b/llvm/test/CodeGen/LoongArch/intrinsic-la64.ll
@@ -178,6 +178,7 @@
 define void @csrrd_d_noret() {
 ; CHECK-LABEL: csrrd_d_noret:
 ; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    csrrd $a0, 1
 ; CHECK-NEXT:    ret
 entry:
   %0 = tail call i64 @llvm.loongarch.csrrd.d(i32 1)
@@ -239,6 +240,7 @@
 define void @iocsrrd_d_noret(i32 %a) {
 ; CHECK-LABEL: iocsrrd_d_noret:
 ; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    iocsrrd.d $a0, $a0
 ; CHECK-NEXT:    ret
 entry:
   %0 = tail call i64 @llvm.loongarch.iocsrrd.d(i32 %a)
diff --git a/llvm/test/CodeGen/LoongArch/intrinsic.ll b/llvm/test/CodeGen/LoongArch/intrinsic.ll
--- a/llvm/test/CodeGen/LoongArch/intrinsic.ll
+++ b/llvm/test/CodeGen/LoongArch/intrinsic.ll
@@ -103,6 +103,7 @@
 define void @csrrd_w_noret() {
 ; CHECK-LABEL: csrrd_w_noret:
 ; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    csrrd $a0, 1
 ; CHECK-NEXT:    ret
 entry:
   %0 = tail call i32 @llvm.loongarch.csrrd.w(i32 1)
@@ -184,6 +185,7 @@
 define void @iocsrrd_b_noret(i32 %a) {
 ; CHECK-LABEL: iocsrrd_b_noret:
 ; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    iocsrrd.b $a0, $a0
 ; CHECK-NEXT:    ret
 entry:
   %0 = tail call i32 @llvm.loongarch.iocsrrd.b(i32 %a)
@@ -193,6 +195,7 @@
 define void @iocsrrd_h_noret(i32 %a) {
 ; CHECK-LABEL: iocsrrd_h_noret:
 ; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    iocsrrd.h $a0, $a0
 ; CHECK-NEXT:    ret
 entry:
   %0 = tail call i32 @llvm.loongarch.iocsrrd.h(i32 %a)
@@ -202,6 +205,7 @@
 define void @iocsrrd_w_noret(i32 %a) {
 ; CHECK-LABEL: iocsrrd_w_noret:
 ; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:    iocsrrd.w $a0, $a0
 ; CHECK-NEXT:    ret
 entry:
   %0 = tail call i32 @llvm.loongarch.iocsrrd.w(i32 %a)