diff --git a/llvm/lib/Target/AMDGPU/SIISelLowering.cpp b/llvm/lib/Target/AMDGPU/SIISelLowering.cpp
--- a/llvm/lib/Target/AMDGPU/SIISelLowering.cpp
+++ b/llvm/lib/Target/AMDGPU/SIISelLowering.cpp
@@ -3198,21 +3198,6 @@
                               "unsupported required tail call to function ");
   }
 
-  if (AMDGPU::isShader(CallConv)) {
-    // Note the issue is with the CC of the called function, not of the call
-    // itself.
-    return lowerUnhandledCall(CLI, InVals,
-                              "unsupported call to a shader function ");
-  }
-
-  if (AMDGPU::isShader(MF.getFunction().getCallingConv()) &&
-      CallConv != CallingConv::AMDGPU_Gfx) {
-    // Only allow calls with specific calling conventions.
-    return lowerUnhandledCall(CLI, InVals,
-                              "unsupported calling convention for call from "
-                              "graphics shader of function ");
-  }
-
   if (IsTailCall) {
     IsTailCall = isEligibleForTailCallOptimization(
       Callee, CallConv, IsVarArg, Outs, OutVals, Ins, DAG);
diff --git a/llvm/test/CodeGen/AMDGPU/call-c-function.ll b/llvm/test/CodeGen/AMDGPU/call-c-function.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/AMDGPU/call-c-function.ll
@@ -0,0 +1,13 @@
+; NOTE: Assertions have been autogenerated by utils/update_mir_test_checks.py
+; RUN: llc -global-isel=0 -stop-after=finalize-isel -mtriple=amdgcn-mesa-mesa3d -mcpu=gfx900 -verify-machineinstrs -o - %s | FileCheck -enable-var-scope %s
+
+; Test that we don't explode on calls from shaders to functions with the C calling convention.
+
+define amdgpu_ps void @amdgpu_ps_call_default_cc() {
+  ; CHECK-LABEL: name: amdgpu_ps_call_default_cc
+  ; CHECK: bb.0.main_body:
+  ; CHECK-NEXT:   S_ENDPGM 0
+main_body:
+  call void null()
+  ret void
+}
diff --git a/llvm/test/CodeGen/AMDGPU/unsupported-calls.ll b/llvm/test/CodeGen/AMDGPU/unsupported-calls.ll
--- a/llvm/test/CodeGen/AMDGPU/unsupported-calls.ll
+++ b/llvm/test/CodeGen/AMDGPU/unsupported-calls.ll
@@ -62,7 +62,7 @@
   ret i32 %call
 }
 
-; GCN: :0:0: in function test_c_call_from_shader i32 (): unsupported calling convention for call from graphics shader of function defined_function
+; GCN-NOT: in function test_c_call_from_shader{{.*}}unsupported
 ; R600: in function test_c_call{{.*}}: unsupported call to function defined_function
 define amdgpu_ps i32 @test_c_call_from_shader() {
   %call = call i32 @defined_function(i32 0)