diff --git a/clang/docs/ReleaseNotes.rst b/clang/docs/ReleaseNotes.rst
--- a/clang/docs/ReleaseNotes.rst
+++ b/clang/docs/ReleaseNotes.rst
@@ -370,6 +370,7 @@
 - Clang now diagnoses unexpected tokens after a
   ``#pragma clang|GCC diagnostic push|pop`` directive.
   (`#13920: <https://github.com/llvm/llvm-project/issues/13920>`_)
+- Clang now does not try to analyze cast validity on variables with dependent alignment (`#63007: <https://github.com/llvm/llvm-project/issues/63007>`_).
 
 Bug Fixes in This Version
 -------------------------
diff --git a/clang/lib/Sema/SemaChecking.cpp b/clang/lib/Sema/SemaChecking.cpp
--- a/clang/lib/Sema/SemaChecking.cpp
+++ b/clang/lib/Sema/SemaChecking.cpp
@@ -16351,8 +16351,12 @@
     if (auto *VD = dyn_cast<VarDecl>(cast<DeclRefExpr>(E)->getDecl())) {
       // FIXME: If VD is captured by copy or is an escaping __block variable,
       // use the alignment of VD's type.
-      if (!VD->getType()->isReferenceType())
+      if (!VD->getType()->isReferenceType()) {
+        // Dependent alignment cannot be resolved -> bail out.
+        if (VD->hasDependentAlignment())
+          break;
         return std::make_pair(Ctx.getDeclAlign(VD), CharUnits::Zero());
+      }
       if (VD->hasInit())
         return getBaseAlignmentAndOffsetFromLValue(VD->getInit(), Ctx);
     }
diff --git a/clang/test/SemaCXX/warn-cast-align.cpp b/clang/test/SemaCXX/warn-cast-align.cpp
--- a/clang/test/SemaCXX/warn-cast-align.cpp
+++ b/clang/test/SemaCXX/warn-cast-align.cpp
@@ -44,6 +44,11 @@
   c = IntPtr(P);
 }
 
+template <class A> void DependentAlign() {
+  alignas(A) int lut[]{};
+  (long *)lut; // expected-warning {{cast from 'int *' to 'long *'}}
+}
+
 struct __attribute__((aligned(16))) AlignedS {
   char m[16];
 };