Index: clang/lib/CodeGen/CGCall.cpp
===================================================================
--- clang/lib/CodeGen/CGCall.cpp
+++ clang/lib/CodeGen/CGCall.cpp
@@ -5183,11 +5183,17 @@
             V->getType()->isIntegerTy())
           V = Builder.CreateZExt(V, ArgInfo.getCoerceToType());
 
-        // If the argument doesn't match, perform a bitcast to coerce it.  This
-        // can happen due to trivial type mismatches.
+        // If the argument doesn't match, perform a either a bitcast or an
+        // address space cast to coerce it. This can happen either due to
+        // trivial type mismatches or valid address space mismatches
+        // (e.g. global -> generic; GEPs into VTTs are an example).
         if (FirstIRArg < IRFuncTy->getNumParams() &&
             V->getType() != IRFuncTy->getParamType(FirstIRArg))
-          V = Builder.CreateBitCast(V, IRFuncTy->getParamType(FirstIRArg));
+          if (V->getType()->isPointerTy())
+            V = Builder.CreateAddrSpaceCast(V,
+                                            IRFuncTy->getParamType(FirstIrArg));
+          else
+            V = Builder.CreateBitCast(V, IRFuncTy->getParamType(FirstIRArg));
 
         if (ArgHasMaybeUndefAttr)
           V = Builder.CreateFreeze(V);