diff --git a/llvm/utils/TableGen/X86FoldTablesEmitter.cpp b/llvm/utils/TableGen/X86FoldTablesEmitter.cpp
--- a/llvm/utils/TableGen/X86FoldTablesEmitter.cpp
+++ b/llvm/utils/TableGen/X86FoldTablesEmitter.cpp
@@ -107,6 +107,21 @@
       OS << SimplifiedAttrs << "},\n";
     }
 
+#ifndef NDEBUG
+    void checkCorrectness() const {
+      // Check that Uses, Defs are same for entries in memory folding table
+      auto &RegInstRec = *RegInst->TheDef;
+      auto &MemInstRec = *MemInst->TheDef;
+      auto ListOfUsesReg = RegInstRec.getValueAsListOfDefs("Uses");
+      auto ListOfUsesMem = MemInstRec.getValueAsListOfDefs("Uses");
+      auto ListOfDefsReg = RegInstRec.getValueAsListOfDefs("Defs");
+      auto ListOfDefsMem = MemInstRec.getValueAsListOfDefs("Defs");
+      if (ListOfUsesReg != ListOfUsesMem || ListOfDefsReg != ListOfDefsMem)
+        llvm::report_fatal_error(
+            "Uses/Defs couldn't be changed after folding " +
+            RegInstRec.getName() + " to " + MemInstRec.getName());
+    }
+#endif
   };
 
   // NOTE: We check the fold tables are sorted in X86InstrFoldTables.cpp by the enum of the
@@ -600,6 +615,22 @@
                  &(Target.getInstruction(MemInstIter)), Entry.Strategy, true);
   }
 
+#ifndef NDEBUG
+  // To Check if the instructions convertion in MemFoldTable change the Uses
+  // and Defs, it's wrong when we convert it and changed its Defs/Uses.
+  auto CheckMemFoldTable = [](const FoldTable &Table) -> void {
+    for (const auto &Record : Table) {
+      auto &FoldEntry = Record.second;
+      FoldEntry.checkCorrectness();
+    }
+  };
+  CheckMemFoldTable(Table2Addr);
+  CheckMemFoldTable(Table0);
+  CheckMemFoldTable(Table1);
+  CheckMemFoldTable(Table2);
+  CheckMemFoldTable(Table3);
+  CheckMemFoldTable(Table4);
+#endif
   // Print all tables.
   printTable(Table2Addr, "Table2Addr", OS);
   printTable(Table0, "Table0", OS);