diff --git a/llvm/lib/Transforms/Instrumentation/GCOVProfiling.cpp b/llvm/lib/Transforms/Instrumentation/GCOVProfiling.cpp
--- a/llvm/lib/Transforms/Instrumentation/GCOVProfiling.cpp
+++ b/llvm/lib/Transforms/Instrumentation/GCOVProfiling.cpp
@@ -919,15 +919,21 @@
           IRBuilder<> Builder(E.Place, E.Place->getFirstInsertionPt());
           Value *V = Builder.CreateConstInBoundsGEP2_64(
               Counters->getValueType(), Counters, 0, I);
+          // Disable sanitizers to decrease size bloat. We don't expect
+          // sanitizers to catch interesting issues.
+          Instruction *Inst;
           if (Options.Atomic) {
-            Builder.CreateAtomicRMW(AtomicRMWInst::Add, V, Builder.getInt64(1),
-                                    MaybeAlign(), AtomicOrdering::Monotonic);
+            Inst = Builder.CreateAtomicRMW(AtomicRMWInst::Add, V,
+                                           Builder.getInt64(1), MaybeAlign(),
+                                           AtomicOrdering::Monotonic);
           } else {
-            Value *Count =
+            LoadInst *OldCount =
                 Builder.CreateLoad(Builder.getInt64Ty(), V, "gcov_ctr");
-            Count = Builder.CreateAdd(Count, Builder.getInt64(1));
-            Builder.CreateStore(Count, V);
+            OldCount->setNoSanitizeMetadata();
+            Value *NewCount = Builder.CreateAdd(OldCount, Builder.getInt64(1));
+            Inst = Builder.CreateStore(NewCount, V);
           }
+          Inst->setNoSanitizeMetadata();
         }
       }
     }
diff --git a/llvm/test/Transforms/GCOVProfiling/nosanitize.ll b/llvm/test/Transforms/GCOVProfiling/nosanitize.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/Transforms/GCOVProfiling/nosanitize.ll
@@ -0,0 +1,34 @@
+;; Ensure that the loads, stores, and atomicrmw adds for gcov have nosanitize metadata.
+; RUN: rm -rf %t && mkdir %t && cd %t
+; RUN: opt < %s -S -passes=insert-gcov-profiling | FileCheck %s
+; RUN: opt < %s -S -passes=insert-gcov-profiling -gcov-atomic-counter | FileCheck %s --check-prefixes=CHECK-ATOMIC-COUNTER
+
+; CHECK-LABEL: void @empty()
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    %gcov_ctr = load i64, ptr @__llvm_gcov_ctr, align 4, !dbg [[DBG:![0-9]+]], !nosanitize [[NOSANITIZE:![0-9]+]]
+; CHECK-NEXT:    %0 = add i64 %gcov_ctr, 1, !dbg [[DBG]]
+; CHECK-NEXT:    store i64 %0, ptr @__llvm_gcov_ctr, align 4, !dbg [[DBG]], !nosanitize [[NOSANITIZE]]
+; CHECK-NEXT:    ret void, !dbg [[DBG]]
+
+; CHECK-ATOMIC-COUNTER-LABEL: void @empty()
+; CHECK-ATOMIC-COUNTER-NEXT:  entry:
+; CHECK-ATOMIC-COUNTER-NEXT:    %0 = atomicrmw add ptr @__llvm_gcov_ctr, i64 1 monotonic, align 8, !dbg [[DBG:![0-9]+]], !nosanitize [[NOSANITIZE:![0-9]+]]
+; CHECK-ATOMIC-COUNTER-NEXT:    ret void, !dbg [[DBG]]
+
+define dso_local void @empty() !dbg !5 {
+entry:
+  ret void, !dbg !8
+}
+
+!llvm.dbg.cu = !{!0}
+!llvm.module.flags = !{!3, !4}
+
+!0 = distinct !DICompileUnit(language: DW_LANG_C99, file: !1, emissionKind: FullDebug, enums: !2)
+!1 = !DIFile(filename: "a.c", directory: "")
+!2 = !{}
+!3 = !{i32 7, !"Dwarf Version", i32 5}
+!4 = !{i32 2, !"Debug Info Version", i32 3}
+!5 = distinct !DISubprogram(name: "empty", scope: !1, file: !1, line: 1, type: !6, scopeLine: 1, flags: DIFlagAllCallsDescribed, spFlags: DISPFlagDefinition | DISPFlagOptimized, unit: !0, retainedNodes: !2)
+!6 = !DISubroutineType(types: !7)
+!7 = !{null}
+!8 = !DILocation(line: 2, column: 1, scope: !5)