diff --git a/llvm/utils/lit/lit/LitConfig.py b/llvm/utils/lit/lit/LitConfig.py
--- a/llvm/utils/lit/lit/LitConfig.py
+++ b/llvm/utils/lit/lit/LitConfig.py
@@ -21,7 +21,7 @@
     """
 
     def __init__(self, progname, path, quiet,
-                 useValgrind, valgrindLeakCheck, valgrindArgs,
+                 useValgrind, valgrindLeakCheck, valgrindArgs, runPrefix,
                  noExecute, debug, isWindows, order,
                  params, config_prefix = None,
                  maxIndividualTestTime = 0,
@@ -35,6 +35,7 @@
         self.useValgrind = bool(useValgrind)
         self.valgrindLeakCheck = bool(valgrindLeakCheck)
         self.valgrindUserArgs = list(valgrindArgs)
+        self.runPrefix = str(runPrefix)
         self.noExecute = noExecute
         self.debug = debug
         self.isWindows = bool(isWindows)
diff --git a/llvm/utils/lit/lit/LitTestCase.py b/llvm/utils/lit/lit/LitTestCase.py
--- a/llvm/utils/lit/lit/LitTestCase.py
+++ b/llvm/utils/lit/lit/LitTestCase.py
@@ -49,6 +49,7 @@
         useValgrind=False,
         valgrindLeakCheck=False,
         valgrindArgs=[],
+        runPrefix='',
         noExecute=False,
         debug=False,
         isWindows=windows,
diff --git a/llvm/utils/lit/lit/TestRunner.py b/llvm/utils/lit/lit/TestRunner.py
--- a/llvm/utils/lit/lit/TestRunner.py
+++ b/llvm/utils/lit/lit/TestRunner.py
@@ -1058,6 +1058,9 @@
             # run on clang with no real loss.
             command = litConfig.valgrindArgs + command
 
+    if litConfig.runPrefix:
+        command = litConfig.runPrefix.split() + command
+
     try:
         out, err, exitCode = lit.util.executeCommand(command, cwd=cwd,
                                        env=test.config.environment,
diff --git a/llvm/utils/lit/lit/cl_arguments.py b/llvm/utils/lit/lit/cl_arguments.py
--- a/llvm/utils/lit/lit/cl_arguments.py
+++ b/llvm/utils/lit/lit/cl_arguments.py
@@ -108,6 +108,12 @@
             help="Specify an extra argument for valgrind",
             action="append",
             default=[])
+    execution_group.add_argument("--run-prefix",
+            dest="runPrefix",
+            default='',
+            metavar="PREFIX",
+            help="Prefix test invocations with the given tool. This is typically "
+                 "used to run cross-compiled tests within a simulator tool.")
     execution_group.add_argument("--time-tests",
             help="Track elapsed wall time for each test",
             action="store_true")
diff --git a/llvm/utils/lit/lit/formats/googletest.py b/llvm/utils/lit/lit/formats/googletest.py
--- a/llvm/utils/lit/lit/formats/googletest.py
+++ b/llvm/utils/lit/lit/formats/googletest.py
@@ -129,6 +129,9 @@
         if litConfig.useValgrind:
             cmd = litConfig.valgrindArgs + cmd
 
+        if litConfig.runPrefix:
+            cmd = litConfig.runPrefix.split() + cmd
+
         if litConfig.noExecute:
             return lit.Test.PASS, ''
 
diff --git a/llvm/utils/lit/lit/main.py b/llvm/utils/lit/lit/main.py
--- a/llvm/utils/lit/lit/main.py
+++ b/llvm/utils/lit/lit/main.py
@@ -34,6 +34,7 @@
         useValgrind=opts.useValgrind,
         valgrindLeakCheck=opts.valgrindLeakCheck,
         valgrindArgs=opts.valgrindArgs,
+        runPrefix=opts.runPrefix,
         noExecute=opts.noExecute,
         debug=opts.debug,
         isWindows=is_windows,
diff --git a/llvm/utils/lit/tests/unit/TestRunner.py b/llvm/utils/lit/tests/unit/TestRunner.py
--- a/llvm/utils/lit/tests/unit/TestRunner.py
+++ b/llvm/utils/lit/tests/unit/TestRunner.py
@@ -30,6 +30,7 @@
                                              useValgrind=False,
                                              valgrindLeakCheck=False,
                                              valgrindArgs=[],
+                                             runPrefix='',
                                              noExecute=False,
                                              debug=False,
                                              isWindows=(