diff --git a/llvm/lib/Transforms/InstCombine/InstCombineCompares.cpp b/llvm/lib/Transforms/InstCombine/InstCombineCompares.cpp
--- a/llvm/lib/Transforms/InstCombine/InstCombineCompares.cpp
+++ b/llvm/lib/Transforms/InstCombine/InstCombineCompares.cpp
@@ -6577,6 +6577,39 @@
     if (Instruction *NI = foldSelectICmp(I.getSwappedPredicate(), SI, Op0, I))
       return NI;
 
+  // In case of a comparison with two select instructions having the same
+  // condition, check whether one of the resulting branches can be simplified.
+  // If so, just compare the other branch and select the appropriate result.
+  // For example:
+  //   %tmp1 = select i1 %cmp, i32 %y, i32 %x
+  //   %tmp2 = select i1 %cmp, i32 %z, i32 %x
+  //   %cmp2 = icmp slt i32 %tmp2, %tmp1
+  // The icmp will result false for the false value of selects and the result
+  // will depend upon the comparison of true values of selects if %cmp is
+  // true. Thus, transform this into:
+  //   %cmp = icmp slt i32 %y, %z
+  //   %sel = select i1 %cond, i1 %cmp, i1 false
+  // This handles similar cases to transform.
+  {
+    Value *Cond1, *Cond2, *A, *B, *C, *D;
+    if (match(Op0, m_Select(m_Value(Cond1), m_Value(A), m_Value(B))) &&
+        match(Op1, m_Select(m_Value(Cond2), m_Value(C), m_Value(D))) &&
+        Cond1 == Cond2) {
+      // Check whether comparison of TrueValues can be simplified
+      if (Value *Res = simplifyICmpInst(Pred, A, C, SQ)) {
+        Builder.SetInsertPoint(&I);
+        Value *NewICMP = Builder.CreateICmp(Pred, B, D);
+        return SelectInst::Create(Cond1, Res, NewICMP);
+      }
+      // Check whether comparison of FalseValues can be simplified
+      if (Value *Res = simplifyICmpInst(Pred, B, D, SQ)) {
+        Builder.SetInsertPoint(&I);
+        Value *NewICMP = Builder.CreateICmp(Pred, A, C);
+        return SelectInst::Create(Cond1, NewICMP, Res);
+      }
+    }
+  }
+
   // Try to optimize equality comparisons against alloca-based pointers.
   if (Op0->getType()->isPointerTy() && I.isEquality()) {
     assert(Op1->getType()->isPointerTy() && "Comparing pointer with non-pointer?");
diff --git a/llvm/test/Transforms/InstCombine/icmp-with-selects.ll b/llvm/test/Transforms/InstCombine/icmp-with-selects.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/Transforms/InstCombine/icmp-with-selects.ll
@@ -0,0 +1,77 @@
+; NOTE: Assertions have been autogenerated by utils/update_test_checks.py UTC_ARGS: --version 2
+; RUN: opt < %s -passes=instcombine -S | FileCheck %s
+
+define i1 @_Z3fooib(i32 noundef %param, i1 noundef zeroext %cond) {
+; CHECK-LABEL: define i1 @_Z3fooib
+; CHECK-SAME: (i32 noundef [[PARAM:%.*]], i1 noundef zeroext [[COND:%.*]]) {
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    ret i1 false
+;
+entry:
+  %cond1 = select i1 %cond, i32 1, i32 %param
+  %cond6 = select i1 %cond, i32 9, i32 %param
+  %cmp = icmp slt i32 %cond6, %cond1
+  ret i1 %cmp
+}
+
+define i1 @_Z4foo1ib(i32 noundef %param, i1 noundef zeroext %cond) {
+; CHECK-LABEL: define i1 @_Z4foo1ib
+; CHECK-SAME: (i32 noundef [[PARAM:%.*]], i1 noundef zeroext [[COND:%.*]]) {
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    [[NOT_COND:%.*]] = xor i1 [[COND]], true
+; CHECK-NEXT:    ret i1 [[NOT_COND]]
+;
+entry:
+  %cond1 = select i1 %cond, i32 1, i32 %param
+  %cond6 = select i1 %cond, i32 9, i32 %param
+  %cmp = icmp eq i32 %cond6, %cond1
+  ret i1 %cmp
+}
+
+define i1 @_Z4foo2iiib(i32 noundef %val1, i32 noundef %val2, i32 noundef %param, i1 noundef zeroext %cond) {
+; CHECK-LABEL: define i1 @_Z4foo2iiib
+; CHECK-SAME: (i32 noundef [[VAL1:%.*]], i32 noundef [[VAL2:%.*]], i32 noundef [[PARAM:%.*]], i1 noundef zeroext [[COND:%.*]]) {
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    [[TMP0:%.*]] = icmp slt i32 [[VAL2]], [[VAL1]]
+; CHECK-NEXT:    [[CMP:%.*]] = and i1 [[TMP0]], [[COND]]
+; CHECK-NEXT:    ret i1 [[CMP]]
+;
+entry:
+  %cond1 = select i1 %cond, i32 %val1, i32 %param
+  %cond6 = select i1 %cond, i32 %val2, i32 %param
+  %cmp = icmp slt i32 %cond6, %cond1
+  ret i1 %cmp
+}
+
+define i1 @_Z4foo3iiib(i32 noundef %val1, i32 noundef %val2, i32 noundef %param, i1 noundef zeroext %cond) {
+; CHECK-LABEL: define i1 @_Z4foo3iiib
+; CHECK-SAME: (i32 noundef [[VAL1:%.*]], i32 noundef [[VAL2:%.*]], i32 noundef [[PARAM:%.*]], i1 noundef zeroext [[COND:%.*]]) {
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    [[TMP0:%.*]] = icmp sgt i32 [[VAL2]], [[VAL1]]
+; CHECK-NEXT:    [[NOT_COND:%.*]] = xor i1 [[COND]], true
+; CHECK-NEXT:    [[CMP:%.*]] = and i1 [[TMP0]], [[NOT_COND]]
+; CHECK-NEXT:    ret i1 [[CMP]]
+;
+entry:
+  %cond1 = select i1 %cond, i32 %param, i32 %val1
+  %cond6 = select i1 %cond, i32 %param, i32 %val2
+  %cmp = icmp sgt i32 %cond6, %cond1
+  ret i1 %cmp
+}
+
+define i1 @_Z4foo4iiib(i32 noundef %val1, i32 noundef %val2, i32 noundef %param, i1 noundef zeroext %cond) {
+; CHECK-LABEL: define i1 @_Z4foo4iiib
+; CHECK-SAME: (i32 noundef [[VAL1:%.*]], i32 noundef [[VAL2:%.*]], i32 noundef [[PARAM:%.*]], i1 noundef zeroext [[COND:%.*]]) {
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    [[TMP0:%.*]] = icmp eq i32 [[VAL2]], [[VAL1]]
+; CHECK-NEXT:    [[NOT_COND:%.*]] = xor i1 [[COND]], true
+; CHECK-NEXT:    [[CMP:%.*]] = or i1 [[TMP0]], [[NOT_COND]]
+; CHECK-NEXT:    ret i1 [[CMP]]
+;
+entry:
+  %cond1 = select i1 %cond, i32 %val1, i32 %param
+  %cond6 = select i1 %cond, i32 %val2, i32 %param
+  %cmp = icmp eq i32 %cond6, %cond1
+  ret i1 %cmp
+}
+