diff --git a/openmp/docs/design/Runtimes.rst b/openmp/docs/design/Runtimes.rst
--- a/openmp/docs/design/Runtimes.rst
+++ b/openmp/docs/design/Runtimes.rst
@@ -1160,6 +1160,7 @@
 * ``LIBOMPTARGET_AMDGPU_TEAMS_PER_CU``
 * ``LIBOMPTARGET_AMDGPU_MAX_ASYNC_COPY_BYTES``
 * ``LIBOMPTARGET_AMDGPU_NUM_INITIAL_HSA_SIGNALS``
+* ``LIBOMPTARGET_AMDGPU_STREAM_BUSYWAIT``
 
 The environment variables ``LIBOMPTARGET_SHARED_MEMORY_SIZE``,
 ``LIBOMPTARGET_STACK_SIZE`` and ``LIBOMPTARGET_HEAP_SIZE`` are described in
@@ -1238,6 +1239,14 @@
 streams. More HSA signals will be created dynamically throughout the execution
 if needed. The default value is ``64``.
 
+LIBOMPTARGET_AMDGPU_STREAM_BUSYWAIT
+"""""""""""""""""""""""""""""""""""
+
+This environment variable controls the timeout hint in microseconds for the
+HSA wait state within the AMDGPU plugin. For the duration of this value
+the HSA runtime may busy wait. This can reduce overall latency.
+The default value is ``2000000``.
+
 .. _remote_offloading_plugin:
 
 Remote Offloading Plugin:
diff --git a/openmp/libomptarget/plugins-nextgen/amdgpu/src/rtl.cpp b/openmp/libomptarget/plugins-nextgen/amdgpu/src/rtl.cpp
--- a/openmp/libomptarget/plugins-nextgen/amdgpu/src/rtl.cpp
+++ b/openmp/libomptarget/plugins-nextgen/amdgpu/src/rtl.cpp
@@ -511,8 +511,14 @@
   }
 
   /// Wait until the signal gets a zero value.
-  Error wait() const {
-    // TODO: Is it better to use busy waiting or blocking the thread?
+  Error wait(const uint64_t ActiveTimeout = 0) const {
+    if (ActiveTimeout) {
+      hsa_signal_value_t Got = 1;
+      Got = hsa_signal_wait_scacquire(Signal, HSA_SIGNAL_CONDITION_EQ, 0,
+                                      ActiveTimeout, HSA_WAIT_STATE_ACTIVE);
+      if (Got == 0)
+        return Plugin::success();
+    }
     while (hsa_signal_wait_scacquire(Signal, HSA_SIGNAL_CONDITION_EQ, 0,
                                      UINT64_MAX, HSA_WAIT_STATE_BLOCKED) != 0)
       ;
@@ -884,6 +890,9 @@
   /// Mutex to protect stream's management.
   mutable std::mutex Mutex;
 
+  /// Timeout hint for HSA actively waiting for signal value to change
+  const uint64_t StreamBusyWaitMicroseconds;
+
   /// Return the current number of asychronous operations on the stream.
   uint32_t size() const { return NextSlot; }
 
@@ -1247,7 +1256,7 @@
       return Plugin::success();
 
     // Wait until all previous operations on the stream have completed.
-    if (auto Err = Slots[last()].Signal->wait())
+    if (auto Err = Slots[last()].Signal->wait(StreamBusyWaitMicroseconds))
       return Err;
 
     // Reset the stream and perform all pending post actions.
@@ -1555,6 +1564,7 @@
                                1 * 1024 * 1024), // 1MB
         OMPX_InitialNumSignals("LIBOMPTARGET_AMDGPU_NUM_INITIAL_HSA_SIGNALS",
                                64),
+        OMPX_StreamBusyWait("LIBOMPTARGET_AMDGPU_STREAM_BUSYWAIT", 2000000),
         AMDGPUStreamManager(*this), AMDGPUEventManager(*this),
         AMDGPUSignalManager(*this), Agent(Agent), HostDevice(HostDevice),
         Queues() {}
@@ -1679,6 +1689,10 @@
     return Plugin::success();
   }
 
+  const uint64_t getStreamBusyWaitMicroseconds() const {
+    return OMPX_StreamBusyWait;
+  }
+
   Expected<std::unique_ptr<MemoryBuffer>>
   doJITPostProcessing(std::unique_ptr<MemoryBuffer> MB) const override {
 
@@ -1941,7 +1955,7 @@
               Plugin::check(Status, "Error in hsa_amd_memory_async_copy: %s"))
         return Err;
 
-      if (auto Err = Signal.wait())
+      if (auto Err = Signal.wait(getStreamBusyWaitMicroseconds()))
         return Err;
 
       if (auto Err = Signal.deinit())
@@ -1998,7 +2012,7 @@
               Plugin::check(Status, "Error in hsa_amd_memory_async_copy: %s"))
         return Err;
 
-      if (auto Err = Signal.wait())
+      if (auto Err = Signal.wait(getStreamBusyWaitMicroseconds()))
         return Err;
 
       if (auto Err = Signal.deinit())
@@ -2173,6 +2187,12 @@
   /// will be created.
   UInt32Envar OMPX_InitialNumSignals;
 
+  /// Environment variables to set the time to wait in active state before
+  /// switching to blocked state. The default 2000000 busywaits for 2 seconds
+  /// before going into a blocking HSA wait state. The unit for these variables
+  /// are microseconds.
+  UInt32Envar OMPX_StreamBusyWait;
+
   /// Stream manager for AMDGPU streams.
   AMDGPUStreamManagerTy AMDGPUStreamManager;
 
@@ -2267,7 +2287,8 @@
     : Agent(Device.getAgent()), Queue(Device.getNextQueue()),
       SignalManager(Device.getSignalManager()),
       // Initialize the std::deque with some empty positions.
-      Slots(32), NextSlot(0), SyncCycle(0) {}
+      Slots(32), NextSlot(0), SyncCycle(0),
+      StreamBusyWaitMicroseconds(Device.getStreamBusyWaitMicroseconds()) {}
 
 /// Class implementing the AMDGPU-specific functionalities of the global
 /// handler.