diff --git a/llvm/lib/Target/X86/X86ISelLowering.cpp b/llvm/lib/Target/X86/X86ISelLowering.cpp
--- a/llvm/lib/Target/X86/X86ISelLowering.cpp
+++ b/llvm/lib/Target/X86/X86ISelLowering.cpp
@@ -53826,7 +53826,28 @@
         return true;
       }
     }
-
+    // Lookup if there is a negated constant vector in DAG.
+    if (V.getOpcode() == ISD::BUILD_VECTOR && V.hasOneUse() &&
+        ISD::isBuildVectorOfConstantFPSDNodes(V.getNode())) {
+      SmallVector<SDValue, 8> Ops;
+      EVT VT = V.getValueType();
+      EVT EltVT = VT.getVectorElementType();
+      for (auto op : V->op_values()) {
+        if (auto *Cst = dyn_cast<ConstantFPSDNode>(op)) {
+          Ops.push_back(
+              DAG.getConstantFP(-Cst->getValueAPF(), SDLoc(op), EltVT));
+        } else {
+          assert(op.isUndef());
+          Ops.push_back(DAG.getUNDEF(EltVT));
+        }
+      }
+      SDNode *NV =
+          DAG.getNodeIfExists(ISD::BUILD_VECTOR, DAG.getVTList(VT), {Ops});
+      if (NV && !NV->use_empty()) {
+        V.setNode(NV);
+        return true;
+      }
+    }
     return false;
   };
 
diff --git a/llvm/test/CodeGen/X86/fma-fneg-combine-2.ll b/llvm/test/CodeGen/X86/fma-fneg-combine-2.ll
--- a/llvm/test/CodeGen/X86/fma-fneg-combine-2.ll
+++ b/llvm/test/CodeGen/X86/fma-fneg-combine-2.ll
@@ -130,16 +130,18 @@
 ; FMA3-LABEL: negated_constant_v4f64:
 ; FMA3:       # %bb.0:
 ; FMA3-NEXT:    vmovapd {{.*#+}} ymm2 = [-5.0E-1,-5.0E-1,-5.0E-1,-5.0E-1]
-; FMA3-NEXT:    vfmadd213pd {{.*#+}} ymm2 = (ymm0 * ymm2) + ymm1
-; FMA3-NEXT:    vfmadd231pd {{.*#+}} ymm1 = (ymm0 * mem) + ymm1
-; FMA3-NEXT:    vaddpd %ymm1, %ymm2, %ymm0
+; FMA3-NEXT:    vmovapd %ymm2, %ymm3
+; FMA3-NEXT:    vfmadd213pd {{.*#+}} ymm3 = (ymm0 * ymm3) + ymm1
+; FMA3-NEXT:    vfnmadd213pd {{.*#+}} ymm2 = -(ymm0 * ymm2) + ymm1
+; FMA3-NEXT:    vaddpd %ymm2, %ymm3, %ymm0
 ; FMA3-NEXT:    retq
 ;
 ; FMA4-LABEL: negated_constant_v4f64:
 ; FMA4:       # %bb.0:
-; FMA4-NEXT:    vfmaddpd {{.*#+}} ymm2 = (ymm0 * mem) + ymm1
-; FMA4-NEXT:    vfmaddpd {{.*#+}} ymm0 = (ymm0 * mem) + ymm1
-; FMA4-NEXT:    vaddpd %ymm0, %ymm2, %ymm0
+; FMA4-NEXT:    vmovapd {{.*#+}} ymm2 = [-5.0E-1,-5.0E-1,-5.0E-1,-5.0E-1]
+; FMA4-NEXT:    vfmaddpd {{.*#+}} ymm3 = (ymm0 * ymm2) + ymm1
+; FMA4-NEXT:    vfnmaddpd {{.*#+}} ymm0 = -(ymm0 * ymm2) + ymm1
+; FMA4-NEXT:    vaddpd %ymm0, %ymm3, %ymm0
 ; FMA4-NEXT:    retq
   %3 = tail call <4 x double> @llvm.fma.v4f64(<4 x double> %0, <4 x double> <double -5.000000e-01, double -5.000000e-01, double -5.000000e-01, double -5.000000e-01>, <4 x double> %1)
   %4 = tail call <4 x double> @llvm.fma.v4f64(<4 x double> %0, <4 x double> <double 5.000000e-01, double 5.000000e-01, double 5.000000e-01, double 5.000000e-01>, <4 x double> %1)