diff --git a/cross-project-tests/debuginfo-tests/dexter/dex/debugger/Debuggers.py b/cross-project-tests/debuginfo-tests/dexter/dex/debugger/Debuggers.py
--- a/cross-project-tests/debuginfo-tests/dexter/dex/debugger/Debuggers.py
+++ b/cross-project-tests/debuginfo-tests/dexter/dex/debugger/Debuggers.py
@@ -114,6 +114,14 @@
         action='store_true',
         default=False,
         help='pass the debugger paths relative to --source-root-dir')
+    parser.add_argument(
+        '--target-run-args',
+        type=str,
+        metavar='<flags>',
+        default='',
+        help='command line arguments for the test program, in addition to any '
+             'provided by DexCommandLine')
+
 
 def handle_debugger_tool_base_options(context, defaults):  # noqa
     options = context.options
diff --git a/cross-project-tests/debuginfo-tests/dexter/dex/debugger/dbgeng/dbgeng.py b/cross-project-tests/debuginfo-tests/dexter/dex/debugger/dbgeng/dbgeng.py
--- a/cross-project-tests/debuginfo-tests/dexter/dex/debugger/dbgeng/dbgeng.py
+++ b/cross-project-tests/debuginfo-tests/dexter/dex/debugger/dbgeng/dbgeng.py
@@ -96,7 +96,7 @@
         raise NotImplementedError('delete_conditional_breakpoint is not yet implemented by dbgeng')
 
     def launch(self, cmdline):
-        assert len(cmdline) == 0, "Command lines unimplemented for dbgeng right now"
+        assert len(cmdline) == 0 and not self.context.options.target_run_args, "Command lines unimplemented for dbgeng right now"
         # We are, by this point, already launched.
         self.step_info = probe_process.probe_state(self.client)
 
diff --git a/cross-project-tests/debuginfo-tests/dexter/dex/debugger/lldb/LLDB.py b/cross-project-tests/debuginfo-tests/dexter/dex/debugger/lldb/LLDB.py
--- a/cross-project-tests/debuginfo-tests/dexter/dex/debugger/lldb/LLDB.py
+++ b/cross-project-tests/debuginfo-tests/dexter/dex/debugger/lldb/LLDB.py
@@ -9,6 +9,7 @@
 
 import imp
 import os
+import shlex
 from subprocess import CalledProcessError, check_output, STDOUT
 import sys
 
@@ -171,6 +172,8 @@
             self._target.BreakpointDelete(id)
 
     def launch(self, cmdline):
+        if self.context.options.target_run_args:
+          cmdline += shlex.split(self.context.options.target_run_args)
         self._process = self._target.LaunchSimple(cmdline, None, os.getcwd())
         if not self._process or self._process.GetNumThreads() == 0:
             raise DebuggerException('could not launch process')
diff --git a/cross-project-tests/debuginfo-tests/dexter/dex/debugger/visualstudio/VisualStudio.py b/cross-project-tests/debuginfo-tests/dexter/dex/debugger/visualstudio/VisualStudio.py
--- a/cross-project-tests/debuginfo-tests/dexter/dex/debugger/visualstudio/VisualStudio.py
+++ b/cross-project-tests/debuginfo-tests/dexter/dex/debugger/visualstudio/VisualStudio.py
@@ -250,6 +250,8 @@
 
     def launch(self, cmdline):
         cmdline_str = ' '.join(cmdline)
+        if self.context.options.target_run_args:
+          cmdline_str += f" {self.context.options.target_run_args}"
 
         # In a slightly baroque manner, lookup the VS project that runs when
         # you click "run", and set its command line options to the desired
diff --git a/cross-project-tests/debuginfo-tests/dexter/feature_tests/subtools/test/target_run_args.c b/cross-project-tests/debuginfo-tests/dexter/feature_tests/subtools/test/target_run_args.c
new file mode 100644
--- /dev/null
+++ b/cross-project-tests/debuginfo-tests/dexter/feature_tests/subtools/test/target_run_args.c
@@ -0,0 +1,15 @@
+// The dbgeng driver doesn't support --target-run-args yet.
+// UNSUPPORTED: system-windows
+//
+// RUN: %dexter_regression_test --target-run-args "a b 'c d'" -- %s | FileCheck %s
+// CHECK: target_run_args.c:
+
+int main(int argc, const char **argv) {
+  if (argc == 4)
+    return 0; // DexLabel('retline')
+
+  return 1; // DexUnreachable()
+}
+
+// DexExpectWatchValue('argc', '4', on_line=ref('retline'))
+// DexExpectWatchValue('argv[1][0]', "'a'", on_line=ref('retline'))
diff --git a/cross-project-tests/debuginfo-tests/dexter/feature_tests/subtools/test/target_run_args_with_command.c b/cross-project-tests/debuginfo-tests/dexter/feature_tests/subtools/test/target_run_args_with_command.c
new file mode 100644
--- /dev/null
+++ b/cross-project-tests/debuginfo-tests/dexter/feature_tests/subtools/test/target_run_args_with_command.c
@@ -0,0 +1,16 @@
+// The dbgeng driver doesn't support --target-run-args yet.
+// UNSUPPORTED: system-windows
+//
+// RUN: %dexter_regression_test --target-run-args "a b 'c d'" -- %s | FileCheck %s
+// CHECK: target_run_args_with_command.c:
+
+int main(int argc, const char **argv) {
+  if (argc == 6)
+    return 0; // DexLabel('retline')
+
+  return 1; // DexUnreachable()
+}
+
+// DexCommandLine(['e', 'f'])
+// DexExpectWatchValue('argc', '6', on_line=ref('retline'))
+// DexExpectWatchValue('argv[1][0]', "'e'", on_line=ref('retline'))