diff --git a/libcxxabi/CMakeLists.txt b/libcxxabi/CMakeLists.txt
--- a/libcxxabi/CMakeLists.txt
+++ b/libcxxabi/CMakeLists.txt
@@ -245,10 +245,6 @@
 #===============================================================================
 
 # Configure target flags
-if(ZOS)
-  add_flags_if_supported("-fzos-le-char-mode=ebcdic")
-endif()
-
 if (${CMAKE_SYSTEM_NAME} MATCHES "AIX")
   add_flags_if_supported("-mdefault-visibility-export-mapping=explicit")
   set(CMAKE_AIX_EXPORT_ALL_SYMBOLS OFF)