Index: llvm/lib/Transforms/IPO/GlobalOpt.cpp
===================================================================
--- llvm/lib/Transforms/IPO/GlobalOpt.cpp
+++ llvm/lib/Transforms/IPO/GlobalOpt.cpp
@@ -2142,8 +2142,16 @@
     return;
   }
 
+  // Get address space of pointers in the array of pointers.
+  unsigned ElemAddrSpace = 0;
+  const Type *UsedArrayType = V.getValueType();
+
+  if (const auto *VAT = dyn_cast<ArrayType>(UsedArrayType))
+    if (const auto *VEPT = dyn_cast<PointerType>(VAT->getArrayElementType()))
+      ElemAddrSpace = VEPT->getAddressSpace();
+
   // Type of pointer to the array of pointers.
-  PointerType *Int8PtrTy = Type::getInt8PtrTy(V.getContext(), 0);
+  PointerType *Int8PtrTy = Type::getInt8PtrTy(V.getContext(), ElemAddrSpace);
 
   SmallVector<Constant *, 8> UsedArray;
   for (GlobalValue *GV : Init) {
Index: llvm/test/Transforms/GlobalOpt/global-opt-addrspace.ll
===================================================================
--- /dev/null
+++ llvm/test/Transforms/GlobalOpt/global-opt-addrspace.ll
@@ -0,0 +1,58 @@
+; RUN: opt -S -passes=globalopt < %s | FileCheck %s
+;; Check that Global Opt preserves address space of llvm.used and
+;; llvm.compiler.used variables.
+
+; ModuleID = 'global-opt-addrspace.ll'
+source_filename = "device_global_internal_failure.cpp"
+target datalayout = "e-i64:64-v16:16-v24:32-v32:32-v48:64-v96:128-v192:256-v256:256-v512:512-v1024:1024-n8:16:32:64"
+target triple = "spir64-unknown-unknown"
+
+%struct.FakeDeviceGlobal = type { ptr addrspace(4) }
+%class.anon = type { i8 }
+
+$_ZTSZ4mainEUlvE_ = comdat any
+
+@_ZL1C = internal addrspace(1) global %struct.FakeDeviceGlobal zeroinitializer, align 8 #0
+@llvm.compiler.used = appending global [1 x ptr addrspace(4)] [ptr addrspace(4) addrspacecast (ptr addrspace(1) @_ZL1C to ptr addrspace(4))], section "llvm.metadata"
+
+; CHECK: @llvm.compiler.used = appending global [1 x ptr addrspace(4)] [ptr addrspace(4) addrspacecast (ptr addrspace(1) @_ZL1C to ptr addrspace(4))], section "llvm.metadata"
+
+; Function Attrs: convergent mustprogress noinline norecurse optnone
+define weak_odr dso_local spir_kernel void @_ZTSZ4mainEUlvE_() #1 comdat !kernel_arg_buffer_location !5 {
+entry:
+  %0 = alloca %class.anon, align 1
+  %1 = addrspacecast ptr %0 to ptr addrspace(4)
+  call spir_func void @_ZZ4mainENKUlvE_clEv(ptr addrspace(4) noundef align 1 dereferenceable_or_null(1) %1) #3
+  ret void
+}
+
+; Function Attrs: convergent mustprogress noinline norecurse nounwind optnone
+define internal spir_func void @_ZZ4mainENKUlvE_clEv(ptr addrspace(4) noundef align 1 dereferenceable_or_null(1) %this) #2 align 2 {
+entry:
+  %this.addr = alloca ptr addrspace(4), align 8
+  %this.addr.ascast = addrspacecast ptr %this.addr to ptr addrspace(4)
+  store ptr addrspace(4) %this, ptr addrspace(4) %this.addr.ascast, align 8
+  %this1 = load ptr addrspace(4), ptr addrspace(4) %this.addr.ascast, align 8
+  %0 = load ptr addrspace(4), ptr addrspace(4) addrspacecast (ptr addrspace(1) @_ZL1C to ptr addrspace(4)), align 8
+  store i32 42, ptr addrspace(4) %0, align 4
+  ret void
+}
+
+declare dso_local spir_func i32 @_Z18__spirv_ocl_printfPU3AS2Kcz(ptr addrspace(2), ...)
+
+attributes #0 = { "sycl-unique-id"="c5b4ae0b52852573____ZL1C" }
+attributes #1 = { convergent mustprogress noinline norecurse optnone "frame-pointer"="all" "min-legal-vector-width"="0" "no-trapping-math"="true" "stack-protector-buffer-size"="8" "sycl-module-id"="device_global_internal_failure.cpp" "uniform-work-group-size"="true" }
+attributes #2 = { convergent mustprogress noinline norecurse nounwind optnone "frame-pointer"="all" "min-legal-vector-width"="0" "no-trapping-math"="true" "stack-protector-buffer-size"="8" }
+attributes #3 = { convergent }
+
+!llvm.module.flags = !{!0, !1}
+!opencl.spir.version = !{!2}
+!spirv.Source = !{!3}
+!llvm.ident = !{!4}
+
+!0 = !{i32 1, !"wchar_size", i32 4}
+!1 = !{i32 7, !"frame-pointer", i32 2}
+!2 = !{i32 1, i32 2}
+!3 = !{i32 4, i32 100000}
+!4 = !{!"clang version 15.0.0 (https://github.com/intel/llvm.git 537e51b08b74438ed64eb7de6e254922e8ddeaa0)"}
+!5 = !{}