diff --git a/llvm/lib/Transforms/Scalar/SimpleLoopUnswitch.cpp b/llvm/lib/Transforms/Scalar/SimpleLoopUnswitch.cpp
--- a/llvm/lib/Transforms/Scalar/SimpleLoopUnswitch.cpp
+++ b/llvm/lib/Transforms/Scalar/SimpleLoopUnswitch.cpp
@@ -3002,8 +3002,8 @@
   auto *InLoopSucc = Candidate.PendingInjection->InLoopSucc;
   auto *TI = cast<BranchInst>(Candidate.TI);
   auto *BB = Candidate.TI->getParent();
-  assert(InLoopSucc == TI->getSuccessor(0));
-  auto *OutOfLoopSucc = TI->getSuccessor(1);
+  auto *OutOfLoopSucc = InLoopSucc == TI->getSuccessor(0) ? TI->getSuccessor(1)
+                                                          : TI->getSuccessor(0);
   // FIXME: Remove this once limitation on successors is lifted.
   assert(L.contains(InLoopSucc) && "Not supported yet!");
   assert(!L.contains(OutOfLoopSucc) && "Not supported yet!");
diff --git a/llvm/test/Transforms/SimpleLoopUnswitch/inject-invariant-conditions.ll b/llvm/test/Transforms/SimpleLoopUnswitch/inject-invariant-conditions.ll
--- a/llvm/test/Transforms/SimpleLoopUnswitch/inject-invariant-conditions.ll
+++ b/llvm/test/Transforms/SimpleLoopUnswitch/inject-invariant-conditions.ll
@@ -438,6 +438,76 @@
   ret i32 -2
 }
 
+define i32 @test_02_inverse(ptr noundef %p, i32 noundef %n, i32 noundef %limit, ptr noundef %arr, ptr noundef %x_p) {
+; CHECK-LABEL: @test_02_inverse(
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    [[X:%.*]] = load i32, ptr [[X_P:%.*]], align 4, !noundef !0
+; CHECK-NEXT:    [[INJECTED_COND:%.*]] = icmp ule i32 -2147483648, [[X]]
+; CHECK-NEXT:    br i1 [[INJECTED_COND]], label [[LOOP_US:%.*]], label [[LOOP:%.*]]
+; CHECK:       loop.us:
+; CHECK-NEXT:    [[IV_US:%.*]] = phi i32 [ [[IV_NEXT_US:%.*]], [[GUARDED_US:%.*]] ], [ 0, [[ENTRY:%.*]] ]
+; CHECK-NEXT:    [[EL_PTR_US:%.*]] = getelementptr i32, ptr [[P:%.*]], i32 [[IV_US]]
+; CHECK-NEXT:    [[EL_US:%.*]] = load i32, ptr [[EL_PTR_US]], align 4
+; CHECK-NEXT:    [[BOUND_CHECK_US:%.*]] = icmp sge i32 [[EL_US]], 0
+; CHECK-NEXT:    br i1 [[BOUND_CHECK_US]], label [[GUARDED_US]], label [[COMMON_RET:%.*]], !prof [[PROF1]]
+; CHECK:       guarded.us:
+; CHECK-NEXT:    [[RANGE_CHECK_US:%.*]] = icmp uge i32 [[EL_US]], [[X]]
+; CHECK-NEXT:    [[ARR_PTR_US:%.*]] = getelementptr i32, ptr [[ARR:%.*]], i32 [[EL_US]]
+; CHECK-NEXT:    store i32 [[IV_US]], ptr [[ARR_PTR_US]], align 4
+; CHECK-NEXT:    [[IV_NEXT_US]] = add i32 [[IV_US]], 1
+; CHECK-NEXT:    [[LOOP_COND_US:%.*]] = icmp slt i32 [[IV_NEXT_US]], [[N:%.*]]
+; CHECK-NEXT:    br i1 [[LOOP_COND_US]], label [[LOOP_US]], label [[COMMON_RET]]
+; CHECK:       loop:
+; CHECK-NEXT:    [[IV:%.*]] = phi i32 [ [[IV_NEXT:%.*]], [[BACKEDGE:%.*]] ], [ 0, [[ENTRY]] ]
+; CHECK-NEXT:    [[EL_PTR:%.*]] = getelementptr i32, ptr [[P]], i32 [[IV]]
+; CHECK-NEXT:    [[EL:%.*]] = load i32, ptr [[EL_PTR]], align 4
+; CHECK-NEXT:    [[BOUND_CHECK:%.*]] = icmp sge i32 [[EL]], 0
+; CHECK-NEXT:    br i1 [[BOUND_CHECK]], label [[GUARDED:%.*]], label [[COMMON_RET]], !prof [[PROF1]]
+; CHECK:       guarded:
+; CHECK-NEXT:    [[RANGE_CHECK:%.*]] = icmp uge i32 [[EL]], [[X]]
+; CHECK-NEXT:    br i1 [[RANGE_CHECK]], label [[BACKEDGE]], label [[COMMON_RET]], !llvm.invariant.condition.injection.disabled !0
+; CHECK:       backedge:
+; CHECK-NEXT:    [[ARR_PTR:%.*]] = getelementptr i32, ptr [[ARR]], i32 [[EL]]
+; CHECK-NEXT:    store i32 [[IV]], ptr [[ARR_PTR]], align 4
+; CHECK-NEXT:    [[IV_NEXT]] = add i32 [[IV]], 1
+; CHECK-NEXT:    [[LOOP_COND:%.*]] = icmp slt i32 [[IV_NEXT]], [[N]]
+; CHECK-NEXT:    br i1 [[LOOP_COND]], label [[LOOP]], label [[COMMON_RET]]
+; CHECK:       common.ret:
+; CHECK-NEXT:    [[COMMON_RET_OP:%.*]] = phi i32 [ 0, [[BACKEDGE]] ], [ 0, [[GUARDED_US]] ], [ -1, [[LOOP]] ], [ -1, [[LOOP_US]] ], [ -2, [[GUARDED]] ]
+; CHECK-NEXT:    ret i32 [[COMMON_RET_OP]]
+;
+entry:
+  %x = load i32, ptr %x_p, align 4, !noundef !{}
+  br label %loop
+
+loop:                                             ; preds = %backedge, %entry
+  %iv = phi i32 [ 0, %entry ], [ %iv.next, %backedge ]
+  %el.ptr = getelementptr i32, ptr %p, i32 %iv
+  %el = load i32, ptr %el.ptr, align 4
+  %bound_check = icmp sge i32 %el, 0
+  br i1 %bound_check, label %guarded, label %bound_check_failed, !prof !{!"branch_weights", i32 100, i32 1}
+
+guarded:                                          ; preds = %loop
+  %range_check = icmp uge i32 %el, %x
+  br i1 %range_check, label %range_check_failed, label %backedge, !prof !{!"branch_weights", i32 1, i32 100}
+
+backedge:                                         ; preds = %guarded
+  %arr.ptr = getelementptr i32, ptr %arr, i32 %el
+  store i32 %iv, ptr %arr.ptr, align 4
+  %iv.next = add i32 %iv, 1
+  %loop_cond = icmp slt i32 %iv.next, %n
+  br i1 %loop_cond, label %loop, label %exit
+
+exit:                                             ; preds = %backedge
+  ret i32 0
+
+bound_check_failed:                               ; preds = %loop
+  ret i32 -1
+
+range_check_failed:                               ; preds = %guarded
+  ret i32 -2
+}
+
 define i32 @test_03(ptr noundef %p, i32 noundef %n, i32 noundef %limit, ptr noundef %arr, ptr noundef %x_p) {
 ; CHECK-LABEL: @test_03(
 ; CHECK-NEXT:  entry: