diff --git a/llvm/CMakeLists.txt b/llvm/CMakeLists.txt
--- a/llvm/CMakeLists.txt
+++ b/llvm/CMakeLists.txt
@@ -827,7 +827,7 @@
 set(LLVM_TARGET_TRIPLE_ENV CACHE STRING "The name of environment variable to override default target. Disabled by blank.")
 mark_as_advanced(LLVM_TARGET_TRIPLE_ENV)
 
-if(CMAKE_SYSTEM_NAME MATCHES "BSD|Linux")
+if(CMAKE_SYSTEM_NAME MATCHES "BSD|Linux|OS390")
   set(LLVM_ENABLE_PER_TARGET_RUNTIME_DIR_default ON)
 else()
   set(LLVM_ENABLE_PER_TARGET_RUNTIME_DIR_default OFF)