diff --git a/clang/lib/CodeGen/CodeGenModule.cpp b/clang/lib/CodeGen/CodeGenModule.cpp
--- a/clang/lib/CodeGen/CodeGenModule.cpp
+++ b/clang/lib/CodeGen/CodeGenModule.cpp
@@ -580,20 +580,6 @@
     EmitMainVoidAlias();
 
   if (getTriple().isAMDGPU()) {
-    // Emit reference of __amdgpu_device_library_preserve_asan_functions to
-    // preserve ASAN functions in bitcode libraries.
-    if (LangOpts.Sanitize.has(SanitizerKind::Address)) {
-      auto *FT = llvm::FunctionType::get(VoidTy, {});
-      auto *F = llvm::Function::Create(
-          FT, llvm::GlobalValue::ExternalLinkage,
-          "__amdgpu_device_library_preserve_asan_functions", &getModule());
-      auto *Var = new llvm::GlobalVariable(
-          getModule(), FT->getPointerTo(),
-          /*isConstant=*/true, llvm::GlobalValue::WeakAnyLinkage, F,
-          "__amdgpu_device_library_preserve_asan_functions_ptr", nullptr,
-          llvm::GlobalVariable::NotThreadLocal);
-      addCompilerUsedGlobal(Var);
-    }
     // Emit amdgpu_code_object_version module flag, which is code object version
     // times 100.
     if (getTarget().getTargetOpts().CodeObjectVersion !=
diff --git a/clang/test/CodeGenCUDA/amdgpu-asan.cu b/clang/test/CodeGenCUDA/amdgpu-asan.cu
deleted file mode 100644
--- a/clang/test/CodeGenCUDA/amdgpu-asan.cu
+++ /dev/null
@@ -1,31 +0,0 @@
-// Create a sample address sanitizer bitcode library.
-
-// RUN: %clang_cc1 -x ir -fcuda-is-device -triple amdgcn-amd-amdhsa -emit-llvm-bc \
-// RUN:   -disable-llvm-passes -o %t.asanrtl.bc %S/Inputs/amdgpu-asanrtl.ll
-
-// Check sanitizer runtime library functions survive
-// optimizations without being removed or parameters altered.
-
-// RUN: %clang_cc1 %s -emit-llvm -o - -triple=amdgcn-amd-amdhsa \
-// RUN:   -fcuda-is-device -target-cpu gfx906 -fsanitize=address \
-// RUN:   -mlink-bitcode-file %t.asanrtl.bc -x hip \
-// RUN:   | FileCheck -check-prefixes=ASAN %s
-
-// RUN: %clang_cc1 %s -emit-llvm -o - -triple=amdgcn-amd-amdhsa \
-// RUN:   -fcuda-is-device -target-cpu gfx906 -fsanitize=address \
-// RUN:   -O3 -mlink-bitcode-file %t.asanrtl.bc -x hip \
-// RUN:   | FileCheck -check-prefixes=ASAN %s
-
-// RUN: %clang_cc1 %s -emit-llvm -o - -triple=amdgcn-amd-amdhsa \
-// RUN:   -fcuda-is-device -target-cpu gfx906 -x hip \
-// RUN:   | FileCheck %s
-
-// REQUIRES: amdgpu-registered-target
-
-// ASAN-DAG: define weak void @__amdgpu_device_library_preserve_asan_functions()
-// ASAN-DAG: @__amdgpu_device_library_preserve_asan_functions_ptr = weak addrspace(1) constant ptr @__amdgpu_device_library_preserve_asan_functions
-// ASAN-DAG: @llvm.compiler.used = {{.*}}@__amdgpu_device_library_preserve_asan_functions_ptr
-// ASAN-DAG: define weak void @__asan_report_load1(i64 %{{.*}})
-
-// CHECK-NOT: @__amdgpu_device_library_preserve_asan_functions
-// CHECK-NOT: @__asan_report_load1