diff --git a/openmp/libomptarget/src/omptarget.cpp b/openmp/libomptarget/src/omptarget.cpp
--- a/openmp/libomptarget/src/omptarget.cpp
+++ b/openmp/libomptarget/src/omptarget.cpp
@@ -586,7 +586,7 @@
     if (getParentIndex(ArgTypes[I]) < 0 && NextI < ArgNum &&
         getParentIndex(ArgTypes[NextI]) == I) {
       Padding = (int64_t)HstPtrBegin % Alignment;
-      if (Padding) {
+      if (Padding && ((int64_t)HstPtrBegin - (int64_t)HstPtrBase >= Padding)) {
         DP("Using a padding of %" PRId64 " bytes for begin address " DPxMOD
            "\n",
            Padding, DPxPTR(HstPtrBegin));
@@ -940,7 +940,8 @@
     if (getParentIndex(ArgTypes[I]) < 0 && NextI < ArgNum &&
         getParentIndex(ArgTypes[NextI]) == I) {
       int64_t Padding = (int64_t)HstPtrBegin % Alignment;
-      if (Padding) {
+
+      if (Padding && ((int64_t)HstPtrBegin - (int64_t)ArgBases[I] >= Padding)) {
         DP("Using a Padding of %" PRId64 " bytes for begin address " DPxMOD
            "\n",
            Padding, DPxPTR(HstPtrBegin));