diff --git a/compiler-rt/lib/tsan/rtl/tsan_interceptors_posix.cpp b/compiler-rt/lib/tsan/rtl/tsan_interceptors_posix.cpp
--- a/compiler-rt/lib/tsan/rtl/tsan_interceptors_posix.cpp
+++ b/compiler-rt/lib/tsan/rtl/tsan_interceptors_posix.cpp
@@ -1945,7 +1945,15 @@
 
 TSAN_INTERCEPTOR(int, epoll_pwait2, int epfd, void *ev, int cnt, void *timeout,
                  void *sigmask) {
-  SCOPED_TSAN_INTERCEPTOR(epoll_pwait2, epfd, ev, cnt, timeout, sigmask);
+  SCOPED_INTERCEPTOR_RAW(epoll_pwait2, epfd, ev, cnt, timeout, sigmask);
+  // This function is new and may not be present in libc and/or kernel.
+  // Since we effectively add it to libc (as will be probed by the program
+  // using dlsym or a weak function pointer) we need to handle the case
+  // when it's not present in the actual libc.
+  if (!REAL(epoll_pwait2))
+    return 38;  // ENOSYS
+  if (MustIgnoreInterceptor(thr))
+    REAL(epoll_pwait2)(epfd, ev, cnt, timeout, sigmask);
   if (epfd >= 0)
     FdAccess(thr, pc, epfd);
   int res = BLOCK_REAL(epoll_pwait2)(epfd, ev, cnt, timeout, sigmask);