Index: llvm/lib/Target/AMDGPU/AMDGPUCtorDtorLowering.cpp
===================================================================
--- llvm/lib/Target/AMDGPU/AMDGPUCtorDtorLowering.cpp
+++ llvm/lib/Target/AMDGPU/AMDGPUCtorDtorLowering.cpp
@@ -56,16 +56,17 @@
     ConstantArray *GA = dyn_cast<ConstantArray>(GV->getInitializer());
     if (!GA || GA->getNumOperands() == 0)
       return false;
+
     Function *InitOrFiniKernel = createInitOrFiniKernelFunction(M, IsCtor);
     IRBuilder<> IRB(InitOrFiniKernel->getEntryBlock().getTerminator());
+
+    FunctionType *ConstructorTy = InitOrFiniKernel->getFunctionType();
+
     for (Value *V : GA->operands()) {
       auto *CS = cast<ConstantStruct>(V);
-      if (Function *F = dyn_cast<Function>(CS->getOperand(1))) {
-        FunctionCallee Ctor =
-            M.getOrInsertFunction(F->getName(), IRB.getVoidTy());
-        IRB.CreateCall(Ctor);
-      }
+      IRB.CreateCall(ConstructorTy, CS->getOperand(1));
     }
+
     appendToUsed(M, {InitOrFiniKernel});
     return true;
   }
Index: llvm/test/CodeGen/AMDGPU/lower-ctor-dtor-constexpr-alias.ll
===================================================================
--- /dev/null
+++ llvm/test/CodeGen/AMDGPU/lower-ctor-dtor-constexpr-alias.ll
@@ -0,0 +1,53 @@
+; RUN: opt -S -mtriple=amdgcn-- -amdgpu-lower-ctor-dtor %s | FileCheck %s
+
+; Make sure we emit code for constructor entries that aren't direct
+; function calls.
+
+; Check a constructor that's an alias, and an integer literal.
+@llvm.global_ctors = appending addrspace(1) global [2 x { i32, ptr, ptr }] [
+  { i32, ptr, ptr } { i32 1, ptr @foo.alias, i8* null },
+  { i32, ptr, ptr } { i32 1, ptr inttoptr (i64 4096 to ptr), i8* null }
+]
+
+; Check a constantexpr addrspacecast
+@llvm.global_dtors = appending addrspace(1) global [1 x { i32, ptr, ptr }] [
+  { i32, ptr, ptr } { i32 1, ptr addrspacecast (ptr addrspace(1) @bar to ptr), i8* null }
+]
+
+@foo.alias = hidden alias void (), ptr @foo
+
+;.
+; CHECK: @llvm.global_ctors = appending addrspace(1) global [2 x { i32, ptr, ptr }] [{ i32, ptr, ptr } { i32 1, ptr @foo.alias, ptr null }, { i32, ptr, ptr } { i32 1, ptr inttoptr (i64 4096 to ptr), ptr null }]
+; CHECK: @llvm.global_dtors = appending addrspace(1) global [1 x { i32, ptr, ptr }] [{ i32, ptr, ptr } { i32 1, ptr addrspacecast (ptr addrspace(1) @bar to ptr), ptr null }]
+; CHECK: @llvm.used = appending global [2 x ptr] [ptr @amdgcn.device.init, ptr @amdgcn.device.fini], section "llvm.metadata"
+; CHECK: @foo.alias = hidden alias void (), ptr @foo
+;.
+define void @foo() {
+; CHECK-LABEL: @foo(
+; CHECK-NEXT:    ret void
+;
+  ret void
+}
+
+define void @bar() addrspace(1) {
+; CHECK-LABEL: @bar(
+; CHECK-NEXT:    ret void
+;
+  ret void
+}
+
+; CHECK: define amdgpu_kernel void @amdgcn.device.init() #[[ATTR0:[0-9]+]] {
+; CHECK-NEXT: call void @foo.alias()
+; CHECK-NEXT: call void inttoptr (i64 4096 to ptr)()
+; CHECK-NEXT: ret void
+; CHECK-NEXT: }
+
+; CHECK: define amdgpu_kernel void @amdgcn.device.fini() #[[ATTR1:[0-9]+]] {
+; CHECK-NEXT: call void addrspacecast (ptr addrspace(1) @bar to ptr)()
+; CHECK-NEXT: ret void
+; CHECK-NEXT: }
+
+;.
+; CHECK: attributes #[[ATTR0]] = { "device-init" }
+; CHECK: attributes #[[ATTR1]] = { "device-fini" }
+;.