Index: clang/include/clang/Basic/DiagnosticSemaKinds.td
===================================================================
--- clang/include/clang/Basic/DiagnosticSemaKinds.td
+++ clang/include/clang/Basic/DiagnosticSemaKinds.td
@@ -8841,6 +8841,9 @@
 
 // inline asm.
 let CategoryName = "Inline Assembly Issue" in {
+  def err_asm_pmf_through_constraint_not_permitted
+    : Error<"passing pointer-to-member through register constrained inline "
+            "assembly parameter is not permitted">;
   def err_asm_invalid_lvalue_in_output : Error<"invalid lvalue in asm output">;
   def err_asm_invalid_output_constraint : Error<
     "invalid output constraint '%0' in asm">;
Index: clang/lib/Sema/SemaStmtAsm.cpp
===================================================================
--- clang/lib/Sema/SemaStmtAsm.cpp
+++ clang/lib/Sema/SemaStmtAsm.cpp
@@ -377,6 +377,11 @@
 
     Expr *InputExpr = Exprs[i];
 
+    if (InputExpr->getType()->isMemberPointerType())
+      return StmtError(Diag(InputExpr->getBeginLoc(),
+                            diag::err_asm_pmf_through_constraint_not_permitted)
+                       << InputExpr->getSourceRange());
+
     // Referring to parameters is not allowed in naked functions.
     if (CheckNakedParmReference(InputExpr, *this))
       return StmtError();
Index: clang/test/Sema/gnu-asm-pmf.cpp
===================================================================
--- /dev/null
+++ clang/test/Sema/gnu-asm-pmf.cpp
@@ -0,0 +1,49 @@
+// RUN: %clang_cc1 -triple x86_64-unknown-windows-msvc -std=c++2b -fsyntax-only %s -verify
+// RUN: %clang_cc1 -triple x86_64-unknown-windows-itanium -std=c++2b -fsyntax-only %s -verify
+
+struct S {
+  void operator()();
+};
+
+struct T {
+  virtual void operator()();
+};
+
+struct U {
+  static void operator()();
+};
+
+struct V: virtual T {
+  virtual void f();
+};
+
+struct W : virtual V {
+  int i;
+};
+
+struct X {
+  __UINTPTR_TYPE__ ptr;
+  __UINTPTR_TYPE__ adj;
+};
+
+auto L = [](){};
+
+void f() {
+  auto pmf = &S::operator();
+
+  __asm__ __volatile__ ("" : : "r"(&decltype(L)::operator()));
+  // expected-error@-1{{passing pointer-to-member through register constrained inline assembly parameter is not permitted}}
+  __asm__ __volatile__ ("" : : "r"(&S::operator()));
+  // expected-error@-1{{passing pointer-to-member through register constrained inline assembly parameter is not permitted}}
+  __asm__ __volatile__ ("" : : "r"(&T::operator()));
+  // expected-error@-1{{passing pointer-to-member through register constrained inline assembly parameter is not permitted}}
+  __asm__ __volatile__ ("" : : "r"(pmf));
+  // expected-error@-1{{passing pointer-to-member through register constrained inline assembly parameter is not permitted}}
+  __asm__ __volatile__ ("" : : "r"(&W::f));
+  // expected-error@-1{{passing pointer-to-member through register constrained inline assembly parameter is not permitted}}
+  __asm__ __volatile__ ("" : : "r"(&W::i));
+  // expected-error@-1{{passing pointer-to-member through register constrained inline assembly parameter is not permitted}}
+
+  __asm__ __volatile__ ("" : : "r"(X{0,0}));
+  __asm__ __volatile__ ("" : : "r"(&U::operator()));
+}