diff --git a/llvm/lib/Transforms/Utils/Debugify.cpp b/llvm/lib/Transforms/Utils/Debugify.cpp
--- a/llvm/lib/Transforms/Utils/Debugify.cpp
+++ b/llvm/lib/Transforms/Utils/Debugify.cpp
@@ -243,13 +243,18 @@
 bool llvm::stripDebugifyMetadata(Module &M) {
   bool Changed = false;
 
-  // Remove the llvm.debugify module-level named metadata.
+  // Remove the llvm.debugify and llvm.mir.debugify module-level named metadata.
   NamedMDNode *DebugifyMD = M.getNamedMetadata("llvm.debugify");
   if (DebugifyMD) {
     M.eraseNamedMetadata(DebugifyMD);
     Changed = true;
   }
 
+  if (auto *MIRDebugifyMD = M.getNamedMetadata("llvm.mir.debugify")) {
+    M.eraseNamedMetadata(MIRDebugifyMD);
+    Changed = true;
+  }
+
   // Strip out all debug intrinsics and supporting metadata (subprograms, types,
   // variables, etc).
   Changed |= StripDebugInfo(M);
diff --git a/llvm/test/CodeGen/Generic/MIRDebugify/locations-and-values.mir b/llvm/test/CodeGen/Generic/MIRDebugify/locations-and-values.mir
--- a/llvm/test/CodeGen/Generic/MIRDebugify/locations-and-values.mir
+++ b/llvm/test/CodeGen/Generic/MIRDebugify/locations-and-values.mir
@@ -27,7 +27,7 @@
   ; VALUE: [[VAR1:![0-9]+]] = !DILocalVariable(name: "1"
   ; VALUE: [[VAR2:![0-9]+]] = !DILocalVariable(name: "2"
   ; STRIP-NOT: !llvm.debugify
-  ; STRIP: !llvm.mir.debugify
+  ; STRIP-NOT: !llvm.mir.debugify
 
 ...
 ---