diff --git a/clang/lib/Driver/SanitizerArgs.cpp b/clang/lib/Driver/SanitizerArgs.cpp
--- a/clang/lib/Driver/SanitizerArgs.cpp
+++ b/clang/lib/Driver/SanitizerArgs.cpp
@@ -1256,6 +1256,8 @@
   if (AsanOutlineInstrumentation) {
     CmdArgs.push_back("-mllvm");
     CmdArgs.push_back("-asan-instrumentation-with-call-threshold=0");
+    CmdArgs.push_back("-mllvm");
+    CmdArgs.push_back("-asan-max-inline-poisoning-size=0");
   }
 
   // Only pass the option to the frontend if the user requested,