diff --git a/clang/lib/Driver/ToolChains/ZOS.cpp b/clang/lib/Driver/ToolChains/ZOS.cpp
--- a/clang/lib/Driver/ToolChains/ZOS.cpp
+++ b/clang/lib/Driver/ToolChains/ZOS.cpp
@@ -18,7 +18,13 @@
 using namespace clang;
 
 ZOS::ZOS(const Driver &D, const llvm::Triple &Triple, const ArgList &Args)
-    : ToolChain(D, Triple, Args) {}
+    : ToolChain(D, Triple, Args) {
+  for (Arg *A : Args.filtered(options::OPT_pg)) {
+    auto ArgString = A->getAsString(Args);
+    this->getDriver().Diag(diag::err_drv_unsupported_opt_for_target)
+        << ArgString << Triple.getTriple();
+  }
+}
 
 ZOS::~ZOS() {}
 
diff --git a/clang/test/Driver/zos-profiling-error.c b/clang/test/Driver/zos-profiling-error.c
new file mode 100644
--- /dev/null
+++ b/clang/test/Driver/zos-profiling-error.c
@@ -0,0 +1,4 @@
+// Check failed cases
+
+// RUN: not %clang -target s390x-none-zos -pg -S %s 2>&1 | FileCheck -check-prefix=FAIL-PG-NAME %s
+// FAIL-PG-NAME: error: unsupported option '-pg' for target 's390x-none-zos'