diff --git a/llvm/lib/Transforms/Scalar/ConstraintElimination.cpp b/llvm/lib/Transforms/Scalar/ConstraintElimination.cpp
--- a/llvm/lib/Transforms/Scalar/ConstraintElimination.cpp
+++ b/llvm/lib/Transforms/Scalar/ConstraintElimination.cpp
@@ -209,9 +209,7 @@
              const DataLayout &DL) {
   // Do not reason about pointers where the index size is larger than 64 bits,
   // as the coefficients used to encode constraints are 64 bit integers.
-  unsigned AS =
-      cast<PointerType>(GEP.getPointerOperand()->getType())->getAddressSpace();
-  if (DL.getIndexSizeInBits(AS) > 64)
+  if (DL.getIndexTypeSizeInBits(GEP.getPointerOperand()->getType()) > 64)
     return {};
 
   if (!GEP.isInBounds())
diff --git a/llvm/test/Transforms/ConstraintElimination/geps-ptrvector.ll b/llvm/test/Transforms/ConstraintElimination/geps-ptrvector.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/Transforms/ConstraintElimination/geps-ptrvector.ll
@@ -0,0 +1,14 @@
+; NOTE: Assertions have been autogenerated by utils/update_test_checks.py
+; RUN: opt -passes=constraint-elimination -S %s | FileCheck %s
+
+; Should not crash when GEP pointer operand is a vector.
+define <2 x i1> @test.vectorgep(<2 x ptr> %vec) {
+; CHECK-LABEL: @test.vectorgep(
+; CHECK-NEXT:    [[GEP:%.*]] = getelementptr inbounds i32, <2 x ptr> [[VEC:%.*]], i64 0
+; CHECK-NEXT:    [[COND:%.*]] = icmp ule <2 x ptr> [[GEP]], zeroinitializer
+; CHECK-NEXT:    ret <2 x i1> [[COND]]
+;
+  %gep = getelementptr inbounds i32, <2 x ptr> %vec, i64 0
+  %cond = icmp ule <2 x ptr> %gep, zeroinitializer
+  ret <2 x i1> %cond
+}