diff --git a/llvm/lib/Transforms/InstCombine/InstCombineAddSub.cpp b/llvm/lib/Transforms/InstCombine/InstCombineAddSub.cpp
--- a/llvm/lib/Transforms/InstCombine/InstCombineAddSub.cpp
+++ b/llvm/lib/Transforms/InstCombine/InstCombineAddSub.cpp
@@ -1270,13 +1270,9 @@
 /// Reduce a sequence of masked half-width multiplies to a single multiply.
 /// ((XLow * YHigh) + (YLow * XHigh)) << HalfBits) + (XLow * YLow) --> X * Y
 static Instruction *foldBoxMultiply(BinaryOperator &I) {
-  if (!I.getType()->isIntegerTy())
-    return nullptr;
-
   unsigned BitWidth = I.getType()->getScalarSizeInBits();
-  // Skip the odd bitwidth types and large bitwidth types
-  // TODO: Relax the constraint of wide/vectors types.
-  if ((BitWidth & 0x1) || (BitWidth > 128))
+  // Skip the odd bitwidth types.
+  if ((BitWidth & 0x1))
     return nullptr;
 
   unsigned HalfBits = BitWidth >> 1;
diff --git a/llvm/test/Transforms/InstCombine/mul_fold.ll b/llvm/test/Transforms/InstCombine/mul_fold.ll
--- a/llvm/test/Transforms/InstCombine/mul_fold.ll
+++ b/llvm/test/Transforms/InstCombine/mul_fold.ll
@@ -521,19 +521,10 @@
   ret i128 %retLo
 }
 
-; TODO: Skip vector type
+; Support vector type
 define <2 x i8> @mul_v2i8_low(<2 x i8> %in0, <2 x i8> %in1) {
 ; CHECK-LABEL: @mul_v2i8_low(
-; CHECK-NEXT:    [[IN0LO:%.*]] = and <2 x i8> [[IN0:%.*]], <i8 15, i8 15>
-; CHECK-NEXT:    [[IN0HI:%.*]] = lshr <2 x i8> [[IN0]], <i8 4, i8 4>
-; CHECK-NEXT:    [[IN1LO:%.*]] = and <2 x i8> [[IN1:%.*]], <i8 15, i8 15>
-; CHECK-NEXT:    [[IN1HI:%.*]] = lshr <2 x i8> [[IN1]], <i8 4, i8 4>
-; CHECK-NEXT:    [[M10:%.*]] = mul <2 x i8> [[IN1HI]], [[IN0]]
-; CHECK-NEXT:    [[M01:%.*]] = mul <2 x i8> [[IN0HI]], [[IN1]]
-; CHECK-NEXT:    [[M00:%.*]] = mul nuw <2 x i8> [[IN1LO]], [[IN0LO]]
-; CHECK-NEXT:    [[ADDC:%.*]] = add <2 x i8> [[M10]], [[M01]]
-; CHECK-NEXT:    [[SHL:%.*]] = shl <2 x i8> [[ADDC]], <i8 4, i8 4>
-; CHECK-NEXT:    [[RETLO:%.*]] = add <2 x i8> [[SHL]], [[M00]]
+; CHECK-NEXT:    [[RETLO:%.*]] = mul <2 x i8> [[IN0:%.*]], [[IN1:%.*]]
 ; CHECK-NEXT:    ret <2 x i8> [[RETLO]]
 ;
   %In0Lo = and <2 x i8> %in0, <i8 15, i8 15>
@@ -551,17 +542,11 @@
 
 define <2 x i8> @mul_v2i8_low_one_extra_user(<2 x i8> %in0, <2 x i8> %in1) {
 ; CHECK-LABEL: @mul_v2i8_low_one_extra_user(
-; CHECK-NEXT:    [[IN0LO:%.*]] = and <2 x i8> [[IN0:%.*]], <i8 15, i8 15>
-; CHECK-NEXT:    [[IN0HI:%.*]] = lshr <2 x i8> [[IN0]], <i8 4, i8 4>
+; CHECK-NEXT:    [[IN0HI:%.*]] = lshr <2 x i8> [[IN0:%.*]], <i8 4, i8 4>
 ; CHECK-NEXT:    [[IN1LO:%.*]] = and <2 x i8> [[IN1:%.*]], <i8 15, i8 15>
-; CHECK-NEXT:    [[IN1HI:%.*]] = lshr <2 x i8> [[IN1]], <i8 4, i8 4>
-; CHECK-NEXT:    [[M10:%.*]] = mul <2 x i8> [[IN1HI]], [[IN0]]
 ; CHECK-NEXT:    [[M01:%.*]] = mul nuw <2 x i8> [[IN1LO]], [[IN0HI]]
 ; CHECK-NEXT:    call void @use_v2i8(<2 x i8> [[M01]])
-; CHECK-NEXT:    [[M00:%.*]] = mul nuw <2 x i8> [[IN1LO]], [[IN0LO]]
-; CHECK-NEXT:    [[ADDC:%.*]] = add <2 x i8> [[M10]], [[M01]]
-; CHECK-NEXT:    [[SHL:%.*]] = shl <2 x i8> [[ADDC]], <i8 4, i8 4>
-; CHECK-NEXT:    [[RETLO:%.*]] = add <2 x i8> [[SHL]], [[M00]]
+; CHECK-NEXT:    [[RETLO:%.*]] = mul <2 x i8> [[IN0]], [[IN1]]
 ; CHECK-NEXT:    ret <2 x i8> [[RETLO]]
 ;
   %In0Lo = and <2 x i8> %in0, <i8 15, i8 15>
@@ -578,19 +563,10 @@
   ret <2 x i8> %retLo
 }
 
-; TODO: Support wide width
+; Support wide width
 define i130 @mul130_low(i130 %in0, i130 %in1) {
 ; CHECK-LABEL: @mul130_low(
-; CHECK-NEXT:    [[IN0LO:%.*]] = and i130 [[IN0:%.*]], 36893488147419103231
-; CHECK-NEXT:    [[IN0HI:%.*]] = lshr i130 [[IN0]], 65
-; CHECK-NEXT:    [[IN1LO:%.*]] = and i130 [[IN1:%.*]], 36893488147419103231
-; CHECK-NEXT:    [[IN1HI:%.*]] = lshr i130 [[IN1]], 65
-; CHECK-NEXT:    [[M10:%.*]] = mul i130 [[IN1HI]], [[IN0]]
-; CHECK-NEXT:    [[M01:%.*]] = mul i130 [[IN0HI]], [[IN1]]
-; CHECK-NEXT:    [[M00:%.*]] = mul nuw i130 [[IN1LO]], [[IN0LO]]
-; CHECK-NEXT:    [[ADDC:%.*]] = add i130 [[M10]], [[M01]]
-; CHECK-NEXT:    [[SHL:%.*]] = shl i130 [[ADDC]], 65
-; CHECK-NEXT:    [[RETLO:%.*]] = add i130 [[SHL]], [[M00]]
+; CHECK-NEXT:    [[RETLO:%.*]] = mul i130 [[IN0:%.*]], [[IN1:%.*]]
 ; CHECK-NEXT:    ret i130 [[RETLO]]
 ;
   %In0Lo = and i130 %in0, 36893488147419103231
@@ -609,16 +585,10 @@
 define i130 @mul130_low_one_extra_user(i130 %in0, i130 %in1) {
 ; CHECK-LABEL: @mul130_low_one_extra_user(
 ; CHECK-NEXT:    [[IN0LO:%.*]] = and i130 [[IN0:%.*]], 36893488147419103231
-; CHECK-NEXT:    [[IN0HI:%.*]] = lshr i130 [[IN0]], 65
-; CHECK-NEXT:    [[IN1LO:%.*]] = and i130 [[IN1:%.*]], 36893488147419103231
-; CHECK-NEXT:    [[IN1HI:%.*]] = lshr i130 [[IN1]], 65
+; CHECK-NEXT:    [[IN1HI:%.*]] = lshr i130 [[IN1:%.*]], 65
 ; CHECK-NEXT:    [[M10:%.*]] = mul nuw i130 [[IN1HI]], [[IN0LO]]
 ; CHECK-NEXT:    call void @use130(i130 [[M10]])
-; CHECK-NEXT:    [[M01:%.*]] = mul i130 [[IN0HI]], [[IN1]]
-; CHECK-NEXT:    [[M00:%.*]] = mul nuw i130 [[IN1LO]], [[IN0LO]]
-; CHECK-NEXT:    [[ADDC:%.*]] = add i130 [[M10]], [[M01]]
-; CHECK-NEXT:    [[SHL:%.*]] = shl i130 [[ADDC]], 65
-; CHECK-NEXT:    [[RETLO:%.*]] = add i130 [[SHL]], [[M00]]
+; CHECK-NEXT:    [[RETLO:%.*]] = mul i130 [[IN0]], [[IN1]]
 ; CHECK-NEXT:    ret i130 [[RETLO]]
 ;
   %In0Lo = and i130 %in0, 36893488147419103231
diff --git a/llvm/test/Transforms/InstCombine/mul_full_64.ll b/llvm/test/Transforms/InstCombine/mul_full_64.ll
--- a/llvm/test/Transforms/InstCombine/mul_full_64.ll
+++ b/llvm/test/Transforms/InstCombine/mul_full_64.ll
@@ -448,7 +448,7 @@
   ret i64 %hi
 }
 
-
+; TODO: https://alive2.llvm.org/ce/z/y26zaW
 define i64 @mullo(i64 %x, i64 %y) {
 ; CHECK-LABEL: @mullo(
 ; CHECK-NEXT:    [[XL:%.*]] = and i64 [[X:%.*]], 4294967295