diff --git a/clang/lib/Format/UnwrappedLineParser.cpp b/clang/lib/Format/UnwrappedLineParser.cpp
--- a/clang/lib/Format/UnwrappedLineParser.cpp
+++ b/clang/lib/Format/UnwrappedLineParser.cpp
@@ -751,6 +751,11 @@
       if (!LBraceStack.empty() && LBraceStack.back()->is(BK_Unknown))
         LBraceStack.back()->setBlockKind(BK_Block);
       break;
+    case tok::hash:
+      do {
+        NextTok = Tokens->getNextToken();
+      } while (NextTok->isNot(tok::eof));
+      break;
     default:
       break;
     }
diff --git a/clang/unittests/Format/FormatTest.cpp b/clang/unittests/Format/FormatTest.cpp
--- a/clang/unittests/Format/FormatTest.cpp
+++ b/clang/unittests/Format/FormatTest.cpp
@@ -19970,6 +19970,14 @@
             format("#pragma region TEST(FOO : BAR)", Style));
 }
 
+TEST_F(FormatTest, PragmaRegionShouldNotBeBraceInitializers) {
+  auto Style = getLLVMStyleWithColumns(0);
+  verifyFormat("CxxClass::CxxClass() {\n#pragma region test(hello)\n}", Style);
+  EXPECT_EQ("CxxClass::CxxClass()\n#pragma region TEST(bar: foo)\n{\n#pragma region TEST(foo: bar)\n#pragma endregion\n}\nCxxClass *Hello() {}",
+            format("CxxClass::CxxClass()\n#pragma region TEST(bar: foo)\n{\n  #pragma region TEST(foo: bar)\n  #pragma endregion\n}\nCxxClass* Hello()\n{}", Style));
+
+}
+
 TEST_F(FormatTest, OptimizeBreakPenaltyVsExcess) {
   FormatStyle Style = getLLVMStyleWithColumns(20);