diff --git a/llvm/lib/Transforms/Utils/CallPromotionUtils.cpp b/llvm/lib/Transforms/Utils/CallPromotionUtils.cpp
--- a/llvm/lib/Transforms/Utils/CallPromotionUtils.cpp
+++ b/llvm/lib/Transforms/Utils/CallPromotionUtils.cpp
@@ -385,6 +385,12 @@
 
   auto &DL = Callee->getParent()->getDataLayout();
 
+  if (CB.countOperandBundlesOfType(LLVMContext::OB_ptrauth)) {
+    if (*FailureReason)
+      *FailureReason = "Authenticating calls are unsupported";
+    return false;
+  }
+
   // Check the return type. The callee's return value type must be bitcast
   // compatible with the call site's type.
   Type *CallRetTy = CB.getType();
diff --git a/llvm/test/Transforms/SampleProfile/Inputs/indirect-call.prof b/llvm/test/Transforms/SampleProfile/Inputs/indirect-call.prof
--- a/llvm/test/Transforms/SampleProfile/Inputs/indirect-call.prof
+++ b/llvm/test/Transforms/SampleProfile/Inputs/indirect-call.prof
@@ -34,3 +34,8 @@
  2: foo_inline3:3000
   1: 0
   2: 3000
+branch_prof_ptrauth:4000:0
+ 1: 1000
+ 2: foo_inline3:3000
+  1: 0
+  2: 3000
diff --git a/llvm/test/Transforms/SampleProfile/indirect-call.ll b/llvm/test/Transforms/SampleProfile/indirect-call.ll
--- a/llvm/test/Transforms/SampleProfile/indirect-call.ll
+++ b/llvm/test/Transforms/SampleProfile/indirect-call.ll
@@ -134,6 +134,18 @@
   ret void
 }
 
+; CHECK-LABEL: @branch_prof_ptrauth
+; Make sure that we don't attempt ICP when the call includes an authentication
+; instruction.
+define void @branch_prof_ptrauth(ptr %t0) #0 !dbg !36 {
+  %t1 = alloca ptr
+  store ptr %t0, ptr %t1
+  %t2 = load ptr, ptr %t1
+  ; CHECK-NOT: br i1
+  call void %t2() [ "ptrauth"(i32 0, i64 0) ], !dbg !37
+  ret void
+}
+
 @x = global i32 0, align 4
 @y = global ptr null, align 8
 
@@ -234,3 +246,5 @@
 !33 = distinct !DISubprogram(name: "branch_prof_valid", scope: !1, file: !1, line: 25, unit: !0)
 !34 = !DILocation(line: 27, scope: !33)
 !35 = distinct !DISubprogram(name: "foo_inline3", scope: !1, file: !1, line: 29, unit: !0)
+!36 = distinct !DISubprogram(name: "branch_prof_ptrauth", scope: !1, file: !1, line: 30, unit: !0)
+!37 = !DILocation(line: 32, scope: !36)