diff --git a/llvm/include/llvm/Transforms/IPO/Inliner.h b/llvm/include/llvm/Transforms/IPO/Inliner.h
--- a/llvm/include/llvm/Transforms/IPO/Inliner.h
+++ b/llvm/include/llvm/Transforms/IPO/Inliner.h
@@ -157,6 +157,7 @@
   CGSCCPassManager PM;
   ModulePassManager MPM;
   ModulePassManager AfterCGMPM;
+  bool MPMFinalized;
 };
 } // end namespace llvm
 
diff --git a/llvm/lib/Transforms/IPO/Inliner.cpp b/llvm/lib/Transforms/IPO/Inliner.cpp
--- a/llvm/lib/Transforms/IPO/Inliner.cpp
+++ b/llvm/lib/Transforms/IPO/Inliner.cpp
@@ -1118,7 +1118,7 @@
                                                    InliningAdvisorMode Mode,
                                                    unsigned MaxDevirtIterations)
     : Params(Params), IC(IC), Mode(Mode),
-      MaxDevirtIterations(MaxDevirtIterations) {
+      MaxDevirtIterations(MaxDevirtIterations), MPMFinalized(false) {
   // Run the inliner first. The theory is that we are walking bottom-up and so
   // the callees have already been fully optimized, and we want to inline them
   // into the callers so that our optimizations can reflect that.
@@ -1149,20 +1149,23 @@
     return PreservedAnalyses::all();
   }
 
-  // We wrap the CGSCC pipeline in a devirtualization repeater. This will try
-  // to detect when we devirtualize indirect calls and iterate the SCC passes
-  // in that case to try and catch knock-on inlining or function attrs
-  // opportunities. Then we add it to the module pipeline by walking the SCCs
-  // in postorder (or bottom-up).
-  // If MaxDevirtIterations is 0, we just don't use the devirtualization
-  // wrapper.
-  if (MaxDevirtIterations == 0)
-    MPM.addPass(createModuleToPostOrderCGSCCPassAdaptor(std::move(PM)));
-  else
-    MPM.addPass(createModuleToPostOrderCGSCCPassAdaptor(
-        createDevirtSCCRepeatedPass(std::move(PM), MaxDevirtIterations)));
-
-  MPM.addPass(std::move(AfterCGMPM));
+  if (!MPMFinalized) {
+    // We wrap the CGSCC pipeline in a devirtualization repeater. This will try
+    // to detect when we devirtualize indirect calls and iterate the SCC passes
+    // in that case to try and catch knock-on inlining or function attrs
+    // opportunities. Then we add it to the module pipeline by walking the SCCs
+    // in postorder (or bottom-up).
+    // If MaxDevirtIterations is 0, we just don't use the devirtualization
+    // wrapper.
+    if (MaxDevirtIterations == 0)
+      MPM.addPass(createModuleToPostOrderCGSCCPassAdaptor(std::move(PM)));
+    else
+      MPM.addPass(createModuleToPostOrderCGSCCPassAdaptor(
+          createDevirtSCCRepeatedPass(std::move(PM), MaxDevirtIterations)));
+
+    MPM.addPass(std::move(AfterCGMPM));
+    MPMFinalized = true;
+  }
   MPM.run(M, MAM);
 
   // Discard the InlineAdvisor, a subsequent inlining session should construct