diff --git a/clang/include/clang/Driver/Options.td b/clang/include/clang/Driver/Options.td
--- a/clang/include/clang/Driver/Options.td
+++ b/clang/include/clang/Driver/Options.td
@@ -6025,6 +6025,9 @@
   HelpText<"Disable validation of precompiled headers">,
   MarshallingInfoFlag<PreprocessorOpts<"DisablePCHOrModuleValidation">, "DisableValidationForModuleKind::None">,
   Normalizer<"makeFlagToValueNormalizer(DisableValidationForModuleKind::All)">;
+def fpcm_output_path_independent : Flag<["-"], "fpcm-output-path-independent">,
+  HelpText<"Output a PCM/PCH file that does not write out information about its output path">,
+  MarshallingInfoFlag<FrontendOpts<"OutputPathIndependentPCM">>;
 def fallow_pcm_with_errors : Flag<["-"], "fallow-pcm-with-compiler-errors">,
   HelpText<"Accept a PCM file that was created with compiler errors">,
   MarshallingInfoFlag<FrontendOpts<"AllowPCMWithCompilerErrors">>;
diff --git a/clang/include/clang/Frontend/FrontendOptions.h b/clang/include/clang/Frontend/FrontendOptions.h
--- a/clang/include/clang/Frontend/FrontendOptions.h
+++ b/clang/include/clang/Frontend/FrontendOptions.h
@@ -344,6 +344,10 @@
   /// When using -emit-module, treat the modulemap as a system module.
   unsigned IsSystemModule : 1;
 
+  /// Output a PCM/PCH file that does not write out information about its output
+  /// path.
+  unsigned OutputPathIndependentPCM : 1;
+
   /// Output (and read) PCM files regardless of compiler errors.
   unsigned AllowPCMWithCompilerErrors : 1;
 
@@ -513,7 +517,8 @@
         ASTDumpLookups(false), BuildingImplicitModule(false),
         BuildingImplicitModuleUsesLock(true), ModulesEmbedAllFiles(false),
         IncludeTimestamps(true), UseTemporary(true),
-        AllowPCMWithCompilerErrors(false), TimeTraceGranularity(500) {}
+        OutputPathIndependentPCM(false), AllowPCMWithCompilerErrors(false),
+        TimeTraceGranularity(500) {}
 
   /// getInputKindForExtension - Return the appropriate input kind for a file
   /// extension. For example, "c" would return Language::C.
diff --git a/clang/include/clang/Serialization/ASTWriter.h b/clang/include/clang/Serialization/ASTWriter.h
--- a/clang/include/clang/Serialization/ASTWriter.h
+++ b/clang/include/clang/Serialization/ASTWriter.h
@@ -573,7 +573,8 @@
   ASTFileSignature WriteAST(Sema &SemaRef, StringRef OutputFile,
                             Module *WritingModule, StringRef isysroot,
                             bool hasErrors = false,
-                            bool ShouldCacheASTInMemory = false);
+                            bool ShouldCacheASTInMemory = false,
+                            bool OutputPathIndependent = false);
 
   /// Emit a token.
   void AddToken(const Token &Tok, RecordDataImpl &Record);
@@ -764,6 +765,7 @@
   ASTWriter Writer;
   bool AllowASTWithErrors;
   bool ShouldCacheASTInMemory;
+  bool OutputPathIndependent;
 
 protected:
   ASTWriter &getWriter() { return Writer; }
@@ -776,7 +778,8 @@
                std::shared_ptr<PCHBuffer> Buffer,
                ArrayRef<std::shared_ptr<ModuleFileExtension>> Extensions,
                bool AllowASTWithErrors = false, bool IncludeTimestamps = true,
-               bool ShouldCacheASTInMemory = false);
+               bool ShouldCacheASTInMemory = false,
+               bool OutputPathIndependent = false);
   ~PCHGenerator() override;
 
   void InitializeSema(Sema &S) override { SemaPtr = &S; }
diff --git a/clang/lib/Frontend/FrontendActions.cpp b/clang/lib/Frontend/FrontendActions.cpp
--- a/clang/lib/Frontend/FrontendActions.cpp
+++ b/clang/lib/Frontend/FrontendActions.cpp
@@ -140,7 +140,8 @@
       CI.getPreprocessor(), CI.getModuleCache(), OutputFile, Sysroot, Buffer,
       FrontendOpts.ModuleFileExtensions,
       CI.getPreprocessorOpts().AllowPCHWithCompilerErrors,
-      FrontendOpts.IncludeTimestamps, +CI.getLangOpts().CacheGeneratedPCH));
+      FrontendOpts.IncludeTimestamps, +CI.getLangOpts().CacheGeneratedPCH,
+      FrontendOpts.OutputPathIndependentPCM));
   Consumers.push_back(CI.getPCHContainerWriter().CreatePCHContainerGenerator(
       CI, std::string(InFile), OutputFile, std::move(OS), Buffer));
 
@@ -203,7 +204,9 @@
       /*IncludeTimestamps=*/
       +CI.getFrontendOpts().BuildingImplicitModule,
       /*ShouldCacheASTInMemory=*/
-      +CI.getFrontendOpts().BuildingImplicitModule));
+      +CI.getFrontendOpts().BuildingImplicitModule,
+      /*OutputPathIndependent=*/
+      +CI.getFrontendOpts().OutputPathIndependentPCM));
   Consumers.push_back(CI.getPCHContainerWriter().CreatePCHContainerGenerator(
       CI, std::string(InFile), OutputFile, std::move(OS), Buffer));
   return std::make_unique<MultiplexConsumer>(std::move(Consumers));
diff --git a/clang/lib/Serialization/ASTWriter.cpp b/clang/lib/Serialization/ASTWriter.cpp
--- a/clang/lib/Serialization/ASTWriter.cpp
+++ b/clang/lib/Serialization/ASTWriter.cpp
@@ -4483,7 +4483,8 @@
 ASTFileSignature ASTWriter::WriteAST(Sema &SemaRef, StringRef OutputFile,
                                      Module *WritingModule, StringRef isysroot,
                                      bool hasErrors,
-                                     bool ShouldCacheASTInMemory) {
+                                     bool ShouldCacheASTInMemory,
+                                     bool OutputPathIndependent) {
   WritingAST = true;
 
   ASTHasCompilerErrors = hasErrors;
@@ -4499,8 +4500,9 @@
   Context = &SemaRef.Context;
   PP = &SemaRef.PP;
   this->WritingModule = WritingModule;
-  ASTFileSignature Signature =
-      WriteASTCore(SemaRef, isysroot, OutputFile, WritingModule);
+  ASTFileSignature Signature = WriteASTCore(
+      SemaRef, isysroot, OutputPathIndependent ? StringRef() : OutputFile,
+      WritingModule);
   Context = nullptr;
   PP = nullptr;
   this->WritingModule = nullptr;
diff --git a/clang/lib/Serialization/GeneratePCH.cpp b/clang/lib/Serialization/GeneratePCH.cpp
--- a/clang/lib/Serialization/GeneratePCH.cpp
+++ b/clang/lib/Serialization/GeneratePCH.cpp
@@ -25,13 +25,14 @@
     StringRef OutputFile, StringRef isysroot, std::shared_ptr<PCHBuffer> Buffer,
     ArrayRef<std::shared_ptr<ModuleFileExtension>> Extensions,
     bool AllowASTWithErrors, bool IncludeTimestamps,
-    bool ShouldCacheASTInMemory)
+    bool ShouldCacheASTInMemory, bool OutputPathIndependent)
     : PP(PP), OutputFile(OutputFile), isysroot(isysroot.str()),
       SemaPtr(nullptr), Buffer(std::move(Buffer)), Stream(this->Buffer->Data),
       Writer(Stream, this->Buffer->Data, ModuleCache, Extensions,
              IncludeTimestamps),
       AllowASTWithErrors(AllowASTWithErrors),
-      ShouldCacheASTInMemory(ShouldCacheASTInMemory) {
+      ShouldCacheASTInMemory(ShouldCacheASTInMemory),
+      OutputPathIndependent(OutputPathIndependent) {
   this->Buffer->IsComplete = false;
 }
 
@@ -70,7 +71,7 @@
                       // For serialization we are lenient if the errors were
                       // only warn-as-error kind.
                       PP.getDiagnostics().hasUncompilableErrorOccurred(),
-                      ShouldCacheASTInMemory);
+                      ShouldCacheASTInMemory, OutputPathIndependent);
 
   Buffer->IsComplete = true;
 }
diff --git a/clang/test/PCH/pch-output-path-independent.c b/clang/test/PCH/pch-output-path-independent.c
new file mode 100644
--- /dev/null
+++ b/clang/test/PCH/pch-output-path-independent.c
@@ -0,0 +1,6 @@
+// RUN: rm -rf %t && mkdir -p %t/a %t/b
+
+// RUN: %clang_cc1 -triple x86_64-apple-macos11 -emit-pch %s -o %t/a/t1.pch -fpcm-output-path-independent
+// RUN: %clang_cc1 -triple x86_64-apple-macos11 -emit-pch %s -o %t/b/t2.pch -fpcm-output-path-independent
+
+// RUN: diff %t/a/t1.pch %t/b/t2.pch