diff --git a/bolt/include/bolt/Core/MCPlusBuilder.h b/bolt/include/bolt/Core/MCPlusBuilder.h
--- a/bolt/include/bolt/Core/MCPlusBuilder.h
+++ b/bolt/include/bolt/Core/MCPlusBuilder.h
@@ -370,6 +370,10 @@
     return Analysis->isIndirectBranch(Inst);
   }
 
+  virtual bool isUnknownControlFlow(const MCInst &Inst) const {
+    return !isCall(Inst) && isIndirectBranch(Inst) && !getJumpTable(Inst);
+  }
+
   /// Returns true if the instruction is memory indirect call or jump
   virtual bool isBranchOnMem(const MCInst &Inst) const {
     llvm_unreachable("not implemented");
diff --git a/bolt/lib/Passes/IndirectCallPromotion.cpp b/bolt/lib/Passes/IndirectCallPromotion.cpp
--- a/bolt/lib/Passes/IndirectCallPromotion.cpp
+++ b/bolt/lib/Passes/IndirectCallPromotion.cpp
@@ -947,6 +947,8 @@
 
   if (BB.getKnownExecutionCount() < opts::ExecutionCountThreshold)
     return 0;
+  if (BC.MIB->isUnknownControlFlow(Inst))
+    return 0;
 
   const bool IsJumpTable = BF->getJumpTable(Inst);