diff --git a/llvm/lib/CodeGen/GlobalISel/Localizer.cpp b/llvm/lib/CodeGen/GlobalISel/Localizer.cpp
--- a/llvm/lib/CodeGen/GlobalISel/Localizer.cpp
+++ b/llvm/lib/CodeGen/GlobalISel/Localizer.cpp
@@ -181,6 +181,17 @@
     MI->removeFromParent();
     MBB.insert(II, MI);
     Changed = true;
+
+    // If the instruction (constant) being localized has single user, we can
+    // propagate debug location from user.
+    if (Users.size() == 1) {
+      const auto &DefDL = MI->getDebugLoc();
+      const auto &UserDL = (*Users.begin())->getDebugLoc();
+
+      if ((!DefDL || DefDL.getLine() == 0) && UserDL && UserDL.getLine() != 0) {
+        MI->setDebugLoc(UserDL);
+      }
+    }
   }
   return Changed;
 }
diff --git a/llvm/test/CodeGen/AArch64/GlobalISel/localizer-propagate-debug-loc.mir b/llvm/test/CodeGen/AArch64/GlobalISel/localizer-propagate-debug-loc.mir
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/AArch64/GlobalISel/localizer-propagate-debug-loc.mir
@@ -0,0 +1,141 @@
+# NOTE: Assertions have been autogenerated by utils/update_mir_test_checks.py
+# RUN: llc -O0 %s -global-isel -start-before localizer \
+# RUN:    -stop-after localizer -o - | FileCheck --check-prefix=CHECK %s
+--- |
+  target datalayout = "e-m:o-i64:64-i128:128-n32:64-S128"
+  target triple = "arm64-apple-macosx12.0.0"
+
+  @A = global i32 1234, align 4
+  @B = global i32 5678, align 4
+  @C = global i32 9012, align 4
+
+  define noundef i32 @foo() !dbg !5 {
+    %1 = alloca i32, align 4
+    br i1 false, label %2, label %4
+
+  2:                                                ; preds = %0
+    %3 = load i32, ptr @A, align 4, !dbg !10
+    store volatile i32 %3, ptr %1, align 4
+    br label %9
+
+  4:                                                ; preds = %0
+    br i1 false, label %5, label %8
+
+  5:                                                ; preds = %4
+    %6 = load i32, ptr @B, align 4, !dbg !13
+    store volatile i32 %6, ptr %1, align 4
+    %7 = load i32, ptr @B, align 4, !dbg !16
+    store volatile i32 %7, ptr %1, align 4
+    br label %9
+
+  8:                                                ; preds = %4
+    store i32 3, ptr @C, align 4, !dbg !17
+    br label %9
+
+  9:                                                ; preds = %8, %5, %2
+    ret i32 0
+  }
+
+  !llvm.dbg.cu = !{!0}
+  !llvm.module.flags = !{!2, !3, !4}
+
+  !0 = distinct !DICompileUnit(language: DW_LANG_C_plus_plus_14, file: !1, isOptimized: false, runtimeVersion: 0, emissionKind: FullDebug, splitDebugInlining: false, nameTableKind: None)
+  !1 = !DIFile(filename: "tmp.ll", directory: "/")
+  !2 = !{i32 7, !"Dwarf Version", i32 4}
+  !3 = !{i32 2, !"Debug Info Version", i32 3}
+  !4 = !{i32 1, !"wchar_size", i32 4}
+  !5 = distinct !DISubprogram(name: "foo", scope: !1, file: !1, line: 5, type: !6, scopeLine: 5, flags: DIFlagPrototyped, spFlags: DISPFlagDefinition, unit: !0, retainedNodes: !9)
+  !6 = !DISubroutineType(types: !7)
+  !7 = !{!8}
+  !8 = !DIBasicType(name: "int", size: 32, encoding: DW_ATE_signed)
+  !9 = !{}
+  !10 = !DILocation(line: 9, column: 9, scope: !11)
+  !11 = distinct !DILexicalBlock(scope: !12, file: !1, line: 8, column: 15)
+  !12 = distinct !DILexicalBlock(scope: !5, file: !1, line: 8, column: 7)
+  !13 = !DILocation(line: 11, column: 9, scope: !14)
+  !14 = distinct !DILexicalBlock(scope: !15, file: !1, line: 10, column: 22)
+  !15 = distinct !DILexicalBlock(scope: !12, file: !1, line: 10, column: 14)
+  !16 = !DILocation(line: 12, column: 13, scope: !14)
+  !17 = !DILocation(line: 14, column: 7, scope: !18)
+  !18 = distinct !DILexicalBlock(scope: !15, file: !1, line: 13, column: 10)
+
+...
+---
+name:            foo
+alignment:       4
+legalized:       true
+regBankSelected: true
+tracksRegLiveness: true
+stack:
+  - { id: 0, name: '', type: default, offset: 0, size: 4, alignment: 4,
+      stack-id: default, callee-saved-register: '', callee-saved-restored: true,
+      debug-info-variable: '', debug-info-expression: '', debug-info-location: '' }
+body:             |
+  ; CHECK:   [[ADRP3:%[0-9]+]]:gpr64(p0) = ADRP target-flags(aarch64-page) @A, debug-location !10
+  ; CHECK-NEXT:   [[ADD_LOW3:%[0-9]+]]:gpr(p0) = G_ADD_LOW [[ADRP3]](p0), target-flags(aarch64-pageoff, aarch64-nc) @A, debug-location !10
+  ; CHECK-NEXT:   [[LOAD:%[0-9]+]]:gpr(s32) = G_LOAD [[ADD_LOW3]](p0), debug-location !10 :: (dereferenceable load (s32))
+
+  ; CHECK:   [[ADRP4:%[0-9]+]]:gpr64(p0) = ADRP target-flags(aarch64-page) @B, debug-location !DILocation(line: 0, scope: !14)
+  ; CHECK-NEXT:   [[ADD_LOW4:%[0-9]+]]:gpr(p0) = G_ADD_LOW [[ADRP4]](p0), target-flags(aarch64-pageoff, aarch64-nc) @B, debug-location !DILocation(line: 0, scope: !14)
+  ; CHECK-NEXT:   [[LOAD1:%[0-9]+]]:gpr(s32) = G_LOAD [[ADD_LOW4]](p0), debug-location !13 :: (dereferenceable load (s32))
+
+  ; CHECK:   [[ADRP5:%[0-9]+]]:gpr64(p0) = ADRP target-flags(aarch64-page) @C, debug-location !17
+  ; CHECK-NEXT:   [[ADD_LOW5:%[0-9]+]]:gpr(p0) = G_ADD_LOW [[ADRP5]](p0), target-flags(aarch64-pageoff, aarch64-nc) @C, debug-location !17
+  ; CHECK-NEXT:   [[C5:%[0-9]+]]:gpr(s32) = G_CONSTANT i32 3, debug-location !17
+  ; CHECK-NEXT:   G_STORE [[C5]](s32), [[ADD_LOW5]](p0), debug-location !17 :: (store (s32) into @C)
+  bb.1:
+    successors: %bb.2(0x40000000), %bb.3(0x40000000)
+
+    %2:gpr(s32) = G_CONSTANT i32 3
+    %24:gpr64(p0) = ADRP target-flags(aarch64-page) @C, debug-location !DILocation(line: 0, scope: !18)
+    %3:gpr(p0) = G_ADD_LOW %24(p0), target-flags(aarch64-pageoff, aarch64-nc) @C, debug-location !DILocation(line: 0, scope: !18)
+    %23:gpr64(p0) = ADRP target-flags(aarch64-page) @B, debug-location !DILocation(line: 0, scope: !14)
+    %5:gpr(p0) = G_ADD_LOW %23(p0), target-flags(aarch64-pageoff, aarch64-nc) @B, debug-location !DILocation(line: 0, scope: !14)
+    %22:gpr64(p0) = ADRP target-flags(aarch64-page) @A, debug-location !DILocation(line: 0, scope: !11)
+    %8:gpr(p0) = G_ADD_LOW %22(p0), target-flags(aarch64-pageoff, aarch64-nc) @A, debug-location !DILocation(line: 0, scope: !11)
+    %9:gpr(s32) = G_CONSTANT i32 0
+    %0:gpr(p0) = G_FRAME_INDEX %stack.0
+    %18:gpr(s32) = COPY %9(s32)
+    %19:gpr(s32) = G_CONSTANT i32 1
+    %20:gpr(s32) = G_XOR %18, %19
+    %11:gpr(s1) = G_TRUNC %20(s32)
+    G_BRCOND %11(s1), %bb.3
+    G_BR %bb.2
+
+  bb.2:
+    successors: %bb.6(0x80000000)
+
+    %7:gpr(s32) = G_LOAD %8(p0), debug-location !10 :: (dereferenceable load (s32))
+    G_STORE %7(s32), %0(p0) :: (volatile store (s32) into %ir.1)
+    G_BR %bb.6
+
+  bb.3:
+    successors: %bb.4(0x40000000), %bb.5(0x40000000)
+
+    %14:gpr(s32) = G_CONSTANT i32 0
+    %15:gpr(s32) = G_CONSTANT i32 1
+    %16:gpr(s32) = G_XOR %14, %15
+    %13:gpr(s1) = G_TRUNC %16(s32)
+    G_BRCOND %13(s1), %bb.5
+    G_BR %bb.4
+
+  bb.4:
+    successors: %bb.6(0x80000000)
+
+    %4:gpr(s32) = G_LOAD %5(p0), debug-location !13 :: (dereferenceable load (s32))
+    G_STORE %4(s32), %0(p0) :: (volatile store (s32) into %ir.1)
+    %6:gpr(s32) = G_LOAD %5(p0), debug-location !16 :: (dereferenceable load (s32))
+    G_STORE %6(s32), %0(p0) :: (volatile store (s32) into %ir.1)
+    G_BR %bb.6
+
+  bb.5:
+    successors: %bb.6(0x80000000)
+
+    G_STORE %2(s32), %3(p0), debug-location !17 :: (store (s32) into @C)
+    G_BR %bb.6
+
+  bb.6:
+    $w0 = COPY %9(s32)
+    RET_ReallyLR implicit $w0
+
+...