diff --git a/llvm/lib/Target/X86/X86FastPreTileConfig.cpp b/llvm/lib/Target/X86/X86FastPreTileConfig.cpp
--- a/llvm/lib/Target/X86/X86FastPreTileConfig.cpp
+++ b/llvm/lib/Target/X86/X86FastPreTileConfig.cpp
@@ -663,6 +663,18 @@
   CfgSS = -1;
 
   unsigned NumVirtRegs = MRI->getNumVirtRegs();
+  // Abandon early if there is no tile register to config.
+  bool HasVirtTileReg = false;
+  for (unsigned I = 0, E = NumVirtRegs; I != E; ++I) {
+    Register VirtReg = Register::index2VirtReg(I);
+    if (MRI->getRegClass(VirtReg)->getID() == X86::TILERegClassID) {
+      HasVirtTileReg = true;
+      break;
+    }
+  }
+  if (!HasVirtTileReg)
+    return false;
+
   StackSlotForVirtReg.resize(NumVirtRegs);
   MayLiveAcrossBlocks.clear();
   // We will create register during config. *3 is to make sure