Index: clang/lib/Format/QualifierAlignmentFixer.cpp
===================================================================
--- clang/lib/Format/QualifierAlignmentFixer.cpp
+++ clang/lib/Format/QualifierAlignmentFixer.cpp
@@ -407,6 +407,8 @@
   assert(QualifierToken != tok::identifier && "Unrecognised Qualifier");
 
   for (AnnotatedLine *Line : AnnotatedLines) {
+    if (Line->InPPDirective)
+      continue;
     FormatToken *First = Line->First;
     assert(First);
     if (First->Finalized)
Index: clang/unittests/Format/QualifierFixerTest.cpp
===================================================================
--- clang/unittests/Format/QualifierFixerTest.cpp
+++ clang/unittests/Format/QualifierFixerTest.cpp
@@ -815,6 +815,7 @@
   ReplacementCount = 0;
   EXPECT_EQ(ReplacementCount, 0);
   verifyFormat("static const uint32 foo[] = {0, 31};", Style);
+  verifyFormat("#define MACRO static const", Style);
   EXPECT_EQ(ReplacementCount, 0);
 }