diff --git a/llvm/include/llvm/CodeGen/TargetCallingConv.h b/llvm/include/llvm/CodeGen/TargetCallingConv.h
--- a/llvm/include/llvm/CodeGen/TargetCallingConv.h
+++ b/llvm/include/llvm/CodeGen/TargetCallingConv.h
@@ -46,7 +46,8 @@
     unsigned IsHvaStart : 1;   ///< HVA structure start
     unsigned IsSecArgPass : 1; ///< Second argument
     unsigned MemAlign : 4;     ///< Log 2 of alignment when arg is passed in memory
-                               ///< (including byval/byref)
+                               ///< (including byval/byref). The max alignment is
+                               ///< verified in IR verification.
     unsigned OrigAlign : 5;    ///< Log 2 of original alignment
     unsigned IsInConsecutiveRegsLast : 1;
     unsigned IsInConsecutiveRegs : 1;
diff --git a/llvm/lib/IR/Verifier.cpp b/llvm/lib/IR/Verifier.cpp
--- a/llvm/lib/IR/Verifier.cpp
+++ b/llvm/lib/IR/Verifier.cpp
@@ -279,6 +279,12 @@
 class Verifier : public InstVisitor<Verifier>, VerifierSupport {
   friend class InstVisitor<Verifier>;
 
+  // ISD::ArgFlagsTy::MemAlign only have 4 bits for alignment, so
+  // the alignment size should not exceed 2^15. Since encode(Align)
+  // would plus the shift value by 1, the alignment size should
+  // not exceed 2^14, otherwise it can NOT be properly lowered
+  // in backend.
+  static constexpr unsigned ParamMaxAlignment = 1 << 14;
   DominatorTree DT;
 
   /// When verifying a basic block, keep track of all of the
@@ -3143,6 +3149,21 @@
   Assert(verifyAttributeCount(Attrs, Call.arg_size()),
          "Attribute after last parameter!", Call);
 
+  auto VerifyTypeAlign = [&](Type *Ty, const Twine &Message) {
+    if (!Ty->isSized())
+      return;
+    Align ABIAlign = DL.getABITypeAlign(Ty);
+    Align MaxAlign(ParamMaxAlignment);
+    Assert(ABIAlign < MaxAlign,
+           "Incorrect alignment of " + Message + " to called function!", Call);
+  };
+
+  VerifyTypeAlign(FTy->getReturnType(), "return type");
+  for (unsigned i = 0, e = FTy->getNumParams(); i != e; ++i) {
+    Type *Ty = FTy->getParamType(i);
+    VerifyTypeAlign(Ty, "argument passed");
+  }
+
   Function *Callee =
       dyn_cast<Function>(Call.getCalledOperand()->stripPointerCasts());
   bool IsIntrinsic = Callee && Callee->isIntrinsic();
diff --git a/llvm/test/Verifier/param-align.ll b/llvm/test/Verifier/param-align.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/Verifier/param-align.ll
@@ -0,0 +1,10 @@
+; RUN: not llvm-as < %s 2>&1 | FileCheck %s
+
+; CHECK: Incorrect alignment of argument passed to called function!
+define dso_local void @foo(<8192 x float> noundef %vec) {
+entry:
+  call void @bar(<8192 x float> %vec)
+  ret void
+}
+
+declare dso_local void @bar(<8192 x float>)
diff --git a/llvm/test/Verifier/param-ret-align.ll b/llvm/test/Verifier/param-ret-align.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/Verifier/param-ret-align.ll
@@ -0,0 +1,10 @@
+; RUN: not llvm-as < %s 2>&1 | FileCheck %s
+
+; CHECK: Incorrect alignment of return type to called function!
+define dso_local void @foo() {
+entry:
+  call <8192 x float> @bar()
+  ret void
+}
+
+declare dso_local <8192 x float> @bar()