diff --git a/clang/lib/Frontend/FrontendAction.cpp b/clang/lib/Frontend/FrontendAction.cpp
--- a/clang/lib/Frontend/FrontendAction.cpp
+++ b/clang/lib/Frontend/FrontendAction.cpp
@@ -843,6 +843,21 @@
   if (!CI.InitializeSourceManager(Input))
     return false;
 
+  if (CI.getLangOpts().CPlusPlusModules && Input.getKind().isHeaderUnit() &&
+      Input.getKind().isPreprocessed() && !usesPreprocessorOnly()) {
+    // We have an input filename like foo.iih, but we want to find the right
+    // module name (and original file, to build the map entry).
+    // Check if the first line specifies the original source file name with a
+    // linemarker.
+    std::string PresumedInputFile = std::string(getCurrentFileOrBufferName());
+    ReadOriginalFileName(CI, PresumedInputFile);
+    // Unless the user overrides this, the module name is the name by which the
+    // original file was known.
+    if (CI.getLangOpts().ModuleName.empty())
+      CI.getLangOpts().ModuleName = std::string(PresumedInputFile);
+    CI.getLangOpts().CurrentModule = CI.getLangOpts().ModuleName;
+  }
+
   // For module map files, we first parse the module map and synthesize a
   // "<module-includes>" buffer before more conventional processing.
   if (Input.getKind().getFormat() == InputKind::ModuleMap) {
diff --git a/clang/lib/Sema/SemaModule.cpp b/clang/lib/Sema/SemaModule.cpp
--- a/clang/lib/Sema/SemaModule.cpp
+++ b/clang/lib/Sema/SemaModule.cpp
@@ -109,10 +109,18 @@
     const_cast<LangOptions &>(getLangOpts()).CurrentModule = HUName.str();
   }
 
-  auto &Map = PP.getHeaderSearchInfo().getModuleMap();
   // TODO: Make the C++20 header lookup independent.
-  Module::Header H{getLangOpts().CurrentModule, getLangOpts().CurrentModule,
-                   SourceMgr.getFileEntryForID(SourceMgr.getMainFileID())};
+  // When the input is pre-processed source, we need a file ref to the original
+  // file for the header map.
+  auto F = SourceMgr.getFileManager().getFile(HUName);
+  // For the sake of error recovery (if someone has moved the original header
+  // after creating the pre-processed output) fall back to obtaining the file
+  // ref for the input file, which must be present.
+  if (!F)
+    F = SourceMgr.getFileEntryForID(SourceMgr.getMainFileID());
+  assert(F && "failed to find the header unit source?");
+  Module::Header H{HUName.str(), HUName.str(), *F};
+  auto &Map = PP.getHeaderSearchInfo().getModuleMap();
   Module *Mod = Map.createHeaderUnit(StartOfTU, HUName, H);
   assert(Mod && "module creation should not fail");
   ModuleScopes.push_back({}); // No GMF
diff --git a/clang/test/Modules/cxx20-hu-05.cpp b/clang/test/Modules/cxx20-hu-05.cpp
new file mode 100644
--- /dev/null
+++ b/clang/test/Modules/cxx20-hu-05.cpp
@@ -0,0 +1,32 @@
+// Test macro preservation in C++20 Header Units.
+
+// RUN: rm -rf %t
+// RUN: mkdir -p %t
+// RUN: split-file %s %t
+// RUN: cd %t
+
+// Produce a pre-processed file.
+// RUN: %clang_cc1 -std=c++20 -E -xc++-user-header hu-01.h -o hu-01.iih
+
+// consume that to produce the heder unit.
+// RUN: %clang_cc1 -std=c++20 -emit-header-unit \
+// RUN: -xc++-header-unit-header-cpp-output hu-01.iih -o hu-01.pcm
+
+// check that the header unit is named for the original file, not the .iih.
+// RUN: %clang_cc1 -std=c++20 -module-file-info hu-01.pcm | \
+// RUN: FileCheck --check-prefix=CHECK-HU %s -DTDIR=%t
+
+//--- hu-01.h
+#ifndef __GUARD
+#define __GUARD
+
+int baz(int);
+#define FORTYTWO 42
+
+#define SHOULD_NOT_BE_DEFINED -1
+#undef SHOULD_NOT_BE_DEFINED
+
+#endif // __GUARD
+
+// CHECK-HU:  ====== C++20 Module structure ======
+// CHECK-HU-NEXT:  Header Unit './hu-01.h' is the Primary Module at index #1