diff --git a/llvm/lib/Transforms/IPO/IROutliner.cpp b/llvm/lib/Transforms/IPO/IROutliner.cpp
--- a/llvm/lib/Transforms/IPO/IROutliner.cpp
+++ b/llvm/lib/Transforms/IPO/IROutliner.cpp
@@ -16,8 +16,9 @@
 #include "llvm/Analysis/OptimizationRemarkEmitter.h"
 #include "llvm/Analysis/TargetTransformInfo.h"
 #include "llvm/IR/Attributes.h"
-#include "llvm/IR/DebugInfoMetadata.h"
 #include "llvm/IR/DIBuilder.h"
+#include "llvm/IR/DebugInfo.h"
+#include "llvm/IR/DebugInfoMetadata.h"
 #include "llvm/IR/Dominators.h"
 #include "llvm/IR/Mangler.h"
 #include "llvm/IR/PassManager.h"
@@ -679,6 +680,18 @@
       if (!isa<CallInst>(&Val)) {
         // Remove the debug information for outlined functions.
         Val.setDebugLoc(DebugLoc());
+
+        // Loop info metadata may contain line locations. Update them to have no
+        // value in the new subprogram since the outlined code could be from
+        // several locations.
+        auto updateLoopInfoLoc = [&New](Metadata *MD) -> Metadata * {
+          if (DISubprogram *SP = New.getSubprogram())
+            if (auto *Loc = dyn_cast_or_null<DILocation>(MD))
+              return DILocation::get(New.getContext(), Loc->getLine(),
+                                     Loc->getColumn(), SP, nullptr);
+          return MD;
+        };
+        updateLoopMetadataDebugLocations(Val, updateLoopInfoLoc);
         continue;
       }
 
diff --git a/llvm/test/Transforms/IROutliner/outlining-strip-loop-info.ll b/llvm/test/Transforms/IROutliner/outlining-strip-loop-info.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/Transforms/IROutliner/outlining-strip-loop-info.ll
@@ -0,0 +1,78 @@
+; NOTE: Assertions have been autogenerated by utils/update_test_checks.py UTC_ARGS: --include-generated-funcs
+; RUN: opt -S -verify -iroutliner -ir-outlining-no-cost < %s | FileCheck %s
+
+; Make sure that we strip loop debug info from instructions that are outlined as
+; well as regular debug info.
+
+define void @ham(i64 %arg0, i64 %arg1) !dbg !1 {
+bb0:
+  br label %bb1
+bb1:
+  %phi = phi i64 [ 0, %bb0 ], [ %arg1, %bb1 ]
+  %icmp = icmp ult i64 %phi, %arg0
+  br i1 %icmp, label %bb1, label %bb2, !dbg !7, !llvm.loop !11
+
+bb2:
+  ret void
+}
+
+define void @wombat(i64 %arg0, i64 %arg1) !dbg !13 {
+bb0:
+  br label %bb1
+bb1:
+  %phi = phi i64 [ 0, %bb0 ], [ %arg1, %bb1 ]
+  %icmp = icmp ult i64 %phi, %arg0
+  br i1 %icmp, label %bb1, label %bb2
+
+bb2:
+  ret void
+}
+
+!llvm.module.flags = !{!0}
+!llvm.dbg.cu = !{}
+
+!0 = !{i32 2, !"Debug Info Version", i32 3}
+!1 = distinct !DISubprogram(name: "ham", scope: !2, file: !2, line: 160, type: !3, scopeLine: 161, flags: DIFlagPrototyped, spFlags: DISPFlagDefinition | DISPFlagOptimized, unit: !5)
+!2 = !DIFile(filename: "file", directory: "dir")
+!3 = !DISubroutineType(types: !4)
+!4 = !{}
+!5 = distinct !DICompileUnit(language: DW_LANG_C_plus_plus, file: !6, producer: "ver", isOptimized: true, runtimeVersion: 0, emissionKind: LineTablesOnly, splitDebugInlining: false, nameTableKind: None, sysroot: "sysroot", sdk: "sdk")
+!6 = !DIFile(filename: "file", directory: "dir")
+!7 = !DILocation(line: 354, column: 13, scope: !8, inlinedAt: !10)
+!8 = distinct !DISubprogram(name: "baz", scope: !9, file: !9, line: 345, type: !3, scopeLine: 346, flags: DIFlagPrototyped, spFlags: DISPFlagDefinition | DISPFlagOptimized, unit: !5)
+!9 = !DIFile(filename: "file", directory: "dir")
+!10 = distinct !DILocation(line: 164, column: 15, scope: !1)
+!11 = distinct !{!11, !7, !12}
+!12 = !DILocation(line: 355, column: 37, scope: !8, inlinedAt: !10)
+!13 = distinct !DISubprogram(name: "wombat", scope: !2, file: !2, line: 172, type: !3, scopeLine: 173, flags: DIFlagPrototyped, spFlags: DISPFlagDefinition | DISPFlagOptimized, unit: !5)
+!14 = distinct !DISubprogram(name: "bar", scope: !15, file: !15, line: 219, type: !3, scopeLine: 220, flags: DIFlagPrototyped, spFlags: DISPFlagDefinition | DISPFlagOptimized, unit: !5)
+!15 = !DIFile(filename: "file", directory: "dir")
+
+; CHECK-LABEL: @ham(
+; CHECK-NEXT:  bb0:
+; CHECK-NEXT:    call void @outlined_ir_func_0(i64 [[ARG1:%.*]], i64 [[ARG0:%.*]]), !dbg [[DBG6:![0-9]+]]
+; CHECK-NEXT:    br label [[BB2:%.*]]
+; CHECK:       bb2:
+; CHECK-NEXT:    ret void
+;
+;
+; CHECK-LABEL: @wombat(
+; CHECK-NEXT:  bb0:
+; CHECK-NEXT:    call void @outlined_ir_func_0(i64 [[ARG1:%.*]], i64 [[ARG0:%.*]]), !dbg [[DBG10:![0-9]+]]
+; CHECK-NEXT:    br label [[BB2:%.*]]
+; CHECK:       bb2:
+; CHECK-NEXT:    ret void
+;
+;
+; CHECK-LABEL: define internal void @outlined_ir_func_0(
+; CHECK-NEXT:  newFuncRoot:
+; CHECK-NEXT:    br label [[BB0_TO_OUTLINE:%.*]]
+; CHECK:       bb0_to_outline:
+; CHECK-NEXT:    br label [[BB1:%.*]]
+; CHECK:       bb1:
+; CHECK-NEXT:    [[PHI:%.*]] = phi i64 [ 0, [[BB0_TO_OUTLINE]] ], [ [[TMP0:%.*]], [[BB1]] ]
+; CHECK-NEXT:    [[ICMP:%.*]] = icmp ult i64 [[PHI]], [[TMP1:%.*]]
+; CHECK-NEXT:    br i1 [[ICMP]], label [[BB1]], label [[BB2_EXITSTUB:%.*]], !llvm.loop [[LOOP12:![0-9]+]]
+; CHECK:       bb2.exitStub:
+; CHECK-NEXT:    ret void
+;