diff --git a/lldb/cmake/modules/LLDBConfig.cmake b/lldb/cmake/modules/LLDBConfig.cmake
--- a/lldb/cmake/modules/LLDBConfig.cmake
+++ b/lldb/cmake/modules/LLDBConfig.cmake
@@ -72,6 +72,10 @@
 option(LLDB_SKIP_STRIP "Whether to skip stripping of binaries when installing lldb." OFF)
 option(LLDB_SKIP_DSYM "Whether to skip generating a dSYM when installing lldb." OFF)
 
+set(LLDB_GLOBAL_INIT_DIRECTORY "" CACHE STRING
+  "Path to the global lldbinit directory. Relative paths are resolved relative to the
+  directory containing the LLDB library.")
+
 if (LLDB_USE_SYSTEM_DEBUGSERVER)
   # The custom target for the system debugserver has no install target, so we
   # need to remove it from the LLVM_DISTRIBUTION_COMPONENTS list.
diff --git a/lldb/include/lldb/API/SBCommandInterpreter.h b/lldb/include/lldb/API/SBCommandInterpreter.h
--- a/lldb/include/lldb/API/SBCommandInterpreter.h
+++ b/lldb/include/lldb/API/SBCommandInterpreter.h
@@ -147,6 +147,8 @@
                              const char *help, const char *syntax,
                              const char *auto_repeat_command);
 
+  void SourceInitFileInGlobalDirectory(lldb::SBCommandReturnObject &result);
+
   void SourceInitFileInHomeDirectory(lldb::SBCommandReturnObject &result);
   void SourceInitFileInHomeDirectory(lldb::SBCommandReturnObject &result,
                                      bool is_repl);
diff --git a/lldb/include/lldb/Host/Config.h.cmake b/lldb/include/lldb/Host/Config.h.cmake
--- a/lldb/include/lldb/Host/Config.h.cmake
+++ b/lldb/include/lldb/Host/Config.h.cmake
@@ -53,4 +53,6 @@
 
 #define LLDB_LIBDIR_SUFFIX "${LLVM_LIBDIR_SUFFIX}"
 
+#cmakedefine LLDB_GLOBAL_INIT_DIRECTORY R"(${LLDB_GLOBAL_INIT_DIRECTORY})"
+
 #endif // #ifndef LLDB_HOST_CONFIG_H
diff --git a/lldb/include/lldb/Interpreter/CommandInterpreter.h b/lldb/include/lldb/Interpreter/CommandInterpreter.h
--- a/lldb/include/lldb/Interpreter/CommandInterpreter.h
+++ b/lldb/include/lldb/Interpreter/CommandInterpreter.h
@@ -253,6 +253,7 @@
 
   void SourceInitFileCwd(CommandReturnObject &result);
   void SourceInitFileHome(CommandReturnObject &result, bool is_repl);
+  void SourceInitFileGlobal(CommandReturnObject &result);
 
   bool AddCommand(llvm::StringRef name, const lldb::CommandObjectSP &cmd_sp,
                   bool can_replace);
diff --git a/lldb/source/API/SBCommandInterpreter.cpp b/lldb/source/API/SBCommandInterpreter.cpp
--- a/lldb/source/API/SBCommandInterpreter.cpp
+++ b/lldb/source/API/SBCommandInterpreter.cpp
@@ -423,6 +423,22 @@
   m_opaque_ptr = interpreter;
 }
 
+void SBCommandInterpreter::SourceInitFileInGlobalDirectory(
+    SBCommandReturnObject &result) {
+  LLDB_INSTRUMENT_VA(this, result);
+
+  result.Clear();
+  if (IsValid()) {
+    TargetSP target_sp(m_opaque_ptr->GetDebugger().GetSelectedTarget());
+    std::unique_lock<std::recursive_mutex> lock;
+    if (target_sp)
+      lock = std::unique_lock<std::recursive_mutex>(target_sp->GetAPIMutex());
+    m_opaque_ptr->SourceInitFileGlobal(result.ref());
+  } else {
+    result->AppendError("SBCommandInterpreter is not valid");
+  }
+}
+
 void SBCommandInterpreter::SourceInitFileInHomeDirectory(
     SBCommandReturnObject &result) {
   LLDB_INSTRUMENT_VA(this, result);
diff --git a/lldb/source/API/SBDebugger.cpp b/lldb/source/API/SBDebugger.cpp
--- a/lldb/source/API/SBDebugger.cpp
+++ b/lldb/source/API/SBDebugger.cpp
@@ -236,6 +236,7 @@
     interp.get()->SkipLLDBInitFiles(false);
     interp.get()->SkipAppInitFiles(false);
     SBCommandReturnObject result;
+    interp.SourceInitFileInGlobalDirectory(result);
     interp.SourceInitFileInHomeDirectory(result, false);
   } else {
     interp.get()->SkipLLDBInitFiles(true);
diff --git a/lldb/source/Interpreter/CommandInterpreter.cpp b/lldb/source/Interpreter/CommandInterpreter.cpp
--- a/lldb/source/Interpreter/CommandInterpreter.cpp
+++ b/lldb/source/Interpreter/CommandInterpreter.cpp
@@ -2380,6 +2380,21 @@
   SourceInitFile(FileSpec(init_file.str()), result);
 }
 
+void CommandInterpreter::SourceInitFileGlobal(CommandReturnObject &result) {
+#ifdef LLDB_GLOBAL_INIT_DIRECTORY
+  if (!m_skip_lldbinit_files) {
+    FileSpec init_file(LLDB_GLOBAL_INIT_DIRECTORY);
+    if (init_file)
+      init_file.MakeAbsolute(HostInfo::GetShlibDir());
+
+    init_file.AppendPathComponent("lldbinit");
+    SourceInitFile(init_file, result);
+    return;
+  }
+#endif
+  result.SetStatus(eReturnStatusSuccessFinishNoResult);
+}
+
 const char *CommandInterpreter::GetCommandPrefix() {
   const char *prefix = GetDebugger().GetIOHandlerCommandPrefix();
   return prefix == nullptr ? "" : prefix;
diff --git a/lldb/tools/driver/Driver.cpp b/lldb/tools/driver/Driver.cpp
--- a/lldb/tools/driver/Driver.cpp
+++ b/lldb/tools/driver/Driver.cpp
@@ -452,9 +452,14 @@
 
   SBCommandInterpreter sb_interpreter = m_debugger.GetCommandInterpreter();
 
-  // Before we handle any options from the command line, we parse the
-  // REPL init file or the default file in the user's home directory.
+  // Process lldbinit files before handling any options from the command line.
   SBCommandReturnObject result;
+  sb_interpreter.SourceInitFileInGlobalDirectory(result);
+  if (m_option_data.m_debug_mode) {
+    result.PutError(m_debugger.GetErrorFile());
+    result.PutOutput(m_debugger.GetOutputFile());
+  }
+
   sb_interpreter.SourceInitFileInHomeDirectory(result, m_option_data.m_repl);
   if (m_option_data.m_debug_mode) {
     result.PutError(m_debugger.GetErrorFile());