diff --git a/libcxx/test/configs/apple-libc++-shared.cfg.in b/libcxx/test/configs/apple-libc++-shared.cfg.in
--- a/libcxx/test/configs/apple-libc++-shared.cfg.in
+++ b/libcxx/test/configs/apple-libc++-shared.cfg.in
@@ -13,7 +13,7 @@
     '-isysroot {}'.format('@CMAKE_OSX_SYSROOT@') if '@CMAKE_OSX_SYSROOT@' else ''
 ))
 config.substitutions.append(('%{compile_flags}',
-    '-nostdinc++ -isystem %{install}/include/c++/v1 -I %{libcxx}/test/support'
+    '-nostdinc++ -I %{install}/include/c++/v1 -I %{libcxx}/test/support'
 ))
 config.substitutions.append(('%{link_flags}',
     '-nostdlib++ -L %{install}/lib -lc++'
diff --git a/libcxx/test/configs/ibm-libc++-shared.cfg.in b/libcxx/test/configs/ibm-libc++-shared.cfg.in
--- a/libcxx/test/configs/ibm-libc++-shared.cfg.in
+++ b/libcxx/test/configs/ibm-libc++-shared.cfg.in
@@ -6,7 +6,7 @@
 
 config.substitutions.append(('%{flags}', ''))
 config.substitutions.append(('%{compile_flags}',
-    '-nostdinc++ -D__LIBC_NO_CPP_MATH_OVERLOADS__ -isystem %{install}/include/c++/v1 -I %{libcxx}/test/support'
+    '-nostdinc++ -D__LIBC_NO_CPP_MATH_OVERLOADS__ -I %{install}/include/c++/v1 -I %{libcxx}/test/support'
 ))
 config.substitutions.append(('%{link_flags}',
     '-nostdlib++ -L %{install}/lib -lc++ -lc++abi -latomic -Wl,-bbigtoc'
diff --git a/libcxx/test/configs/llvm-libc++-mingw.cfg.in b/libcxx/test/configs/llvm-libc++-mingw.cfg.in
--- a/libcxx/test/configs/llvm-libc++-mingw.cfg.in
+++ b/libcxx/test/configs/llvm-libc++-mingw.cfg.in
@@ -5,7 +5,7 @@
 
 config.substitutions.append(('%{flags}', ''))
 config.substitutions.append(('%{compile_flags}',
-    '-nostdinc++ -isystem %{include} -isystem %{target-include} -I %{libcxx}/test/support'
+    '-nostdinc++ -I %{include} -I %{target-include} -I %{libcxx}/test/support'
 ))
 config.substitutions.append(('%{link_flags}',
     '-nostdlib++ -L %{lib} -lc++'
diff --git a/libcxx/test/configs/llvm-libc++-shared-clangcl.cfg.in b/libcxx/test/configs/llvm-libc++-shared-clangcl.cfg.in
--- a/libcxx/test/configs/llvm-libc++-shared-clangcl.cfg.in
+++ b/libcxx/test/configs/llvm-libc++-shared-clangcl.cfg.in
@@ -5,7 +5,7 @@
 
 config.substitutions.append(('%{flags}', '--driver-mode=g++'))
 config.substitutions.append(('%{compile_flags}',
-    '-nostdinc++ -isystem %{include} -isystem %{target-include} -I %{libcxx}/test/support -D_CRT_SECURE_NO_WARNINGS -D_CRT_NONSTDC_NO_WARNINGS -D_CRT_STDIO_ISO_WIDE_SPECIFIERS -DNOMINMAX'
+    '-nostdinc++ -I %{include} -I %{target-include} -I %{libcxx}/test/support -D_CRT_SECURE_NO_WARNINGS -D_CRT_NONSTDC_NO_WARNINGS -D_CRT_STDIO_ISO_WIDE_SPECIFIERS -DNOMINMAX'
 ))
 config.substitutions.append(('%{link_flags}',
     '-nostdlib -L %{lib} -lc++ -lmsvcrt -lmsvcprt -loldnames'
diff --git a/libcxx/test/configs/llvm-libc++-shared-gcc.cfg.in b/libcxx/test/configs/llvm-libc++-shared-gcc.cfg.in
--- a/libcxx/test/configs/llvm-libc++-shared-gcc.cfg.in
+++ b/libcxx/test/configs/llvm-libc++-shared-gcc.cfg.in
@@ -6,7 +6,7 @@
 
 config.substitutions.append(('%{flags}', ''))
 config.substitutions.append(('%{compile_flags}',
-    '-nostdinc++ -isystem %{include} -isystem %{target-include} -I %{libcxx}/test/support'
+    '-nostdinc++ -I %{include} -I %{target-include} -I %{libcxx}/test/support'
 ))
 config.substitutions.append(('%{link_flags}',
     '-L %{lib} -Wl,-rpath,%{lib} -nodefaultlibs -lc++ -lm -lgcc_s -lgcc -lpthread -lc -lgcc_s -lgcc -latomic'
diff --git a/libcxx/test/configs/llvm-libc++-shared.cfg.in b/libcxx/test/configs/llvm-libc++-shared.cfg.in
--- a/libcxx/test/configs/llvm-libc++-shared.cfg.in
+++ b/libcxx/test/configs/llvm-libc++-shared.cfg.in
@@ -7,7 +7,7 @@
     '-isysroot {}'.format('@CMAKE_OSX_SYSROOT@') if '@CMAKE_OSX_SYSROOT@' else ''
 ))
 config.substitutions.append(('%{compile_flags}',
-    '-nostdinc++ -isystem %{include} -isystem %{target-include} -I %{libcxx}/test/support'
+    '-nostdinc++ -I %{include} -I %{target-include} -I %{libcxx}/test/support'
 ))
 config.substitutions.append(('%{link_flags}',
     '-nostdlib++ -L %{lib} -Wl,-rpath,%{lib} -lc++ -pthread'
diff --git a/libcxx/test/configs/llvm-libc++-static-clangcl.cfg.in b/libcxx/test/configs/llvm-libc++-static-clangcl.cfg.in
--- a/libcxx/test/configs/llvm-libc++-static-clangcl.cfg.in
+++ b/libcxx/test/configs/llvm-libc++-static-clangcl.cfg.in
@@ -5,7 +5,7 @@
 
 config.substitutions.append(('%{flags}', '--driver-mode=g++'))
 config.substitutions.append(('%{compile_flags}',
-    '-nostdinc++ -isystem %{include} -isystem %{target-include} -I %{libcxx}/test/support -D_CRT_SECURE_NO_WARNINGS -D_CRT_NONSTDC_NO_WARNINGS -D_CRT_STDIO_ISO_WIDE_SPECIFIERS -DNOMINMAX'
+    '-nostdinc++ -I %{include} -I %{target-include} -I %{libcxx}/test/support -D_CRT_SECURE_NO_WARNINGS -D_CRT_NONSTDC_NO_WARNINGS -D_CRT_STDIO_ISO_WIDE_SPECIFIERS -DNOMINMAX'
 ))
 config.substitutions.append(('%{link_flags}',
     '-nostdlib -L %{lib} -llibc++ -lmsvcrt -lmsvcprt -loldnames'
diff --git a/libcxx/test/configs/llvm-libc++-static.cfg.in b/libcxx/test/configs/llvm-libc++-static.cfg.in
--- a/libcxx/test/configs/llvm-libc++-static.cfg.in
+++ b/libcxx/test/configs/llvm-libc++-static.cfg.in
@@ -7,7 +7,7 @@
     '-isysroot {}'.format('@CMAKE_OSX_SYSROOT@') if '@CMAKE_OSX_SYSROOT@' else ''
 ))
 config.substitutions.append(('%{compile_flags}',
-    '-nostdinc++ -isystem %{include} -isystem %{target-include} -I %{libcxx}/test/support'
+    '-nostdinc++ -I %{include} -I %{target-include} -I %{libcxx}/test/support'
 ))
 config.substitutions.append(('%{link_flags}',
     '-nostdlib++ -L %{lib} -lc++ -lc++abi -pthread'
diff --git a/libcxx/test/std/containers/sequences/array/size_and_alignment.pass.cpp b/libcxx/test/std/containers/sequences/array/size_and_alignment.pass.cpp
--- a/libcxx/test/std/containers/sequences/array/size_and_alignment.pass.cpp
+++ b/libcxx/test/std/containers/sequences/array/size_and_alignment.pass.cpp
@@ -20,6 +20,10 @@
 
 #include "test_macros.h"
 
+// Ignore error about requesting a large alignment not being ABI compatible with older AIX systems.
+#if defined(_AIX)
+# pragma clang diagnostic ignored "-Waix-compat"
+#endif
 
 template <class T, size_t Size>
 struct MyArray {