diff --git a/llvm/lib/Target/AMDGPU/SIWholeQuadMode.cpp b/llvm/lib/Target/AMDGPU/SIWholeQuadMode.cpp
--- a/llvm/lib/Target/AMDGPU/SIWholeQuadMode.cpp
+++ b/llvm/lib/Target/AMDGPU/SIWholeQuadMode.cpp
@@ -1591,7 +1591,7 @@
 
   // If we performed any kills then recompute EXEC
   if (!KillInstrs.empty())
-    LIS->removeRegUnit(*MCRegUnitIterator(AMDGPU::EXEC, TRI));
+    LIS->removeAllRegUnitsForPhysReg(AMDGPU::EXEC);
 
   return true;
 }