diff --git a/clang/lib/Format/ContinuationIndenter.cpp b/clang/lib/Format/ContinuationIndenter.cpp
--- a/clang/lib/Format/ContinuationIndenter.cpp
+++ b/clang/lib/Format/ContinuationIndenter.cpp
@@ -485,7 +485,8 @@
     // different LineFormatter would be used otherwise.
     if (Previous.ClosesTemplateDeclaration)
       return Style.AlwaysBreakTemplateDeclarations != FormatStyle::BTDS_No;
-    if (Previous.is(TT_FunctionAnnotationRParen))
+    if (Previous.is(TT_FunctionAnnotationRParen) &&
+        State.Line->Type != LT_PreprocessorDirective)
       return true;
     if (Previous.is(TT_LeadingJavaAnnotation) && Current.isNot(tok::l_paren) &&
         Current.isNot(TT_LeadingJavaAnnotation))
diff --git a/clang/unittests/Format/FormatTest.cpp b/clang/unittests/Format/FormatTest.cpp
--- a/clang/unittests/Format/FormatTest.cpp
+++ b/clang/unittests/Format/FormatTest.cpp
@@ -4804,6 +4804,15 @@
                Style);
 }
 
+TEST_F(FormatTest, FormatMacroWithZeroColumnWidth) {
+  FormatStyle ZeroColumn = getLLVMStyleWithColumns(0);
+
+  // clang-format off
+  verifyFormat("#define A LOOOOOOOOOOOOOOOOOOONG() LOOOOOOOOOOOOOOOOOOONG()\n",
+               ZeroColumn);
+  // clang-format on
+}
+
 TEST_F(FormatTest, LayoutMacroDefinitionsStatementsSpanningBlocks) {
   verifyFormat("#define A \\\n"
                "  f({     \\\n"