diff --git a/clang/lib/Driver/ToolChains/Linux.cpp b/clang/lib/Driver/ToolChains/Linux.cpp
--- a/clang/lib/Driver/ToolChains/Linux.cpp
+++ b/clang/lib/Driver/ToolChains/Linux.cpp
@@ -687,7 +687,7 @@
 }
 
 bool Linux::IsMathErrnoDefault() const {
-  if (getTriple().isAndroid())
+  if (getTriple().isAndroid() || getTriple().isMusl())
     return false;
   return Generic_ELF::IsMathErrnoDefault();
 }
diff --git a/clang/test/Driver/fast-math.c b/clang/test/Driver/fast-math.c
--- a/clang/test/Driver/fast-math.c
+++ b/clang/test/Driver/fast-math.c
@@ -119,6 +119,8 @@
 // RUN:   | FileCheck --check-prefix=CHECK-NO-MATH-ERRNO %s
 // RUN: %clang -### -target x86_64-linux-android -c %s 2>&1 \
 // RUN:   | FileCheck --check-prefix=CHECK-NO-MATH-ERRNO %s
+// RUN: %clang -### -target x86_64-linux-musl -c %s 2>&1 \
+// RUN:   | FileCheck --check-prefix=CHECK-NO-MATH-ERRNO %s
 // RUN: %clang -### -target amdgcn-amd-amdhsa -c %s 2>&1 \
 // RUN:   | FileCheck --check-prefix=CHECK-NO-MATH-ERRNO %s
 // RUN: %clang -### -target amdgcn-amd-amdpal -c %s 2>&1 \