diff --git a/llvm/cmake/platforms/WinMsvc.cmake b/llvm/cmake/platforms/WinMsvc.cmake
--- a/llvm/cmake/platforms/WinMsvc.cmake
+++ b/llvm/cmake/platforms/WinMsvc.cmake
@@ -250,6 +250,11 @@
 list(APPEND _CTF_NATIVE_DEFAULT "-DCMAKE_ASM_COMPILER=${LLVM_NATIVE_TOOLCHAIN}/bin/clang")
 list(APPEND _CTF_NATIVE_DEFAULT "-DCMAKE_C_COMPILER=${LLVM_NATIVE_TOOLCHAIN}/bin/clang")
 list(APPEND _CTF_NATIVE_DEFAULT "-DCMAKE_CXX_COMPILER=${LLVM_NATIVE_TOOLCHAIN}/bin/clang++")
+list(APPEND _CTF_NATIVE_DEFAULT "-DCMAKE_C_FLAGS=\"\"")
+list(APPEND _CTF_NATIVE_DEFAULT "-DCMAKE_CXX_FLAGS=\"\"")
+list(APPEND _CTF_NATIVE_DEFAULT "-DCMAKE_EXE_LINKER_FLAGS=\"\"")
+list(APPEND _CTF_NATIVE_DEFAULT "-DCMAKE_MODULE_LINKER_FLAGS=\"\"")
+list(APPEND _CTF_NATIVE_DEFAULT "-DCMAKE_SHARED_LINKER_FLAGS=\"\"")
 
 set(CROSS_TOOLCHAIN_FLAGS_NATIVE "${_CTF_NATIVE_DEFAULT}" CACHE STRING "")
 
@@ -284,11 +289,11 @@
 # The assignments to the _INITIAL cache variables don't use FORCE, so they'll
 # only be populated on the initial configure, and their values won't change
 # afterward.
-set(_CMAKE_C_FLAGS_INITIAL "${CMAKE_C_FLAGS}" CACHE STRING "")
-set(CMAKE_C_FLAGS "${_CMAKE_C_FLAGS_INITIAL} ${COMPILE_FLAGS}" CACHE STRING "" FORCE)
+set(_CMAKE_C_FLAGS_INITIAL "${CMAKE_C_FLAGS_INIT}" CACHE STRING "")
+set(CMAKE_C_FLAGS_INIT "${_CMAKE_C_FLAGS_INITIAL} ${COMPILE_FLAGS}" CACHE STRING "" FORCE)
 
-set(_CMAKE_CXX_FLAGS_INITIAL "${CMAKE_CXX_FLAGS}" CACHE STRING "")
-set(CMAKE_CXX_FLAGS "${_CMAKE_CXX_FLAGS_INITIAL} ${COMPILE_FLAGS}" CACHE STRING "" FORCE)
+set(_CMAKE_CXX_FLAGS_INITIAL "${CMAKE_CXX_FLAGS_INIT}" CACHE STRING "")
+set(CMAKE_CXX_FLAGS_INIT "${_CMAKE_CXX_FLAGS_INITIAL} ${COMPILE_FLAGS}" CACHE STRING "" FORCE)
 
 set(LINK_FLAGS
     # Prevent CMake from attempting to invoke mt.exe. It only recognizes the slashed form and not the dashed form.
@@ -314,14 +319,14 @@
 string(REPLACE ";" " " LINK_FLAGS "${LINK_FLAGS}")
 
 # See explanation for compiler flags above for the _INITIAL variables.
-set(_CMAKE_EXE_LINKER_FLAGS_INITIAL "${CMAKE_EXE_LINKER_FLAGS}" CACHE STRING "")
-set(CMAKE_EXE_LINKER_FLAGS "${_CMAKE_EXE_LINKER_FLAGS_INITIAL} ${LINK_FLAGS}" CACHE STRING "" FORCE)
+set(_CMAKE_EXE_LINKER_FLAGS_INITIAL "${CMAKE_EXE_LINKER_FLAGS_INIT}" CACHE STRING "")
+set(CMAKE_EXE_LINKER_FLAGS_INIT "${_CMAKE_EXE_LINKER_FLAGS_INITIAL} ${LINK_FLAGS}" CACHE STRING "" FORCE)
 
-set(_CMAKE_MODULE_LINKER_FLAGS_INITIAL "${CMAKE_MODULE_LINKER_FLAGS}" CACHE STRING "")
-set(CMAKE_MODULE_LINKER_FLAGS "${_CMAKE_MODULE_LINKER_FLAGS_INITIAL} ${LINK_FLAGS}" CACHE STRING "" FORCE)
+set(_CMAKE_MODULE_LINKER_FLAGS_INITIAL "${CMAKE_MODULE_LINKER_FLAGS_INIT}" CACHE STRING "")
+set(CMAKE_MODULE_LINKER_FLAGS_INIT "${_CMAKE_MODULE_LINKER_FLAGS_INITIAL} ${LINK_FLAGS}" CACHE STRING "" FORCE)
 
-set(_CMAKE_SHARED_LINKER_FLAGS_INITIAL "${CMAKE_SHARED_LINKER_FLAGS}" CACHE STRING "")
-set(CMAKE_SHARED_LINKER_FLAGS "${_CMAKE_SHARED_LINKER_FLAGS_INITIAL} ${LINK_FLAGS}" CACHE STRING "" FORCE)
+set(_CMAKE_SHARED_LINKER_FLAGS_INITIAL "${CMAKE_SHARED_LINKER_FLAGS_INIT}" CACHE STRING "")
+set(CMAKE_SHARED_LINKER_FLAGS_INIT "${_CMAKE_SHARED_LINKER_FLAGS_INITIAL} ${LINK_FLAGS}" CACHE STRING "" FORCE)
 
 # CMake populates these with a bunch of unnecessary libraries, which requires
 # extra case-correcting symlinks and what not. Instead, let projects explicitly