diff --git a/clang/include/clang/Basic/CodeGenOptions.def b/clang/include/clang/Basic/CodeGenOptions.def
--- a/clang/include/clang/Basic/CodeGenOptions.def
+++ b/clang/include/clang/Basic/CodeGenOptions.def
@@ -231,6 +231,9 @@
 ENUM_CODEGENOPT(SanitizeAddressDtor, llvm::AsanDtorKind, 2,
                 llvm::AsanDtorKind::Global)  ///< Set how ASan global
                                              ///< destructors are emitted.
+CODEGENOPT(SanitizeMemoryParamRetval, 1, 0) ///< Enable detection of uninitialized
+                                            ///< parameters and return values
+                                            ///< in MemorySanitizer
 CODEGENOPT(SanitizeMemoryUseAfterDtor, 1, 0) ///< Enable use-after-delete detection
                                              ///< in MemorySanitizer
 CODEGENOPT(SanitizeCfiCrossDso, 1, 0) ///< Enable cross-dso support in CFI.
diff --git a/clang/include/clang/Driver/Options.td b/clang/include/clang/Driver/Options.td
--- a/clang/include/clang/Driver/Options.td
+++ b/clang/include/clang/Driver/Options.td
@@ -1669,6 +1669,13 @@
       NormalizedValuesScope<"llvm::AsanDtorKind">,
       NormalizedValues<["None", "Global"]>,
       MarshallingInfoEnum<CodeGenOpts<"SanitizeAddressDtor">, "Global">;
+defm sanitize_memory_param_retval
+  : BoolOption<"f", "sanitize-memory-param-retval",
+      CodeGenOpts<"SanitizeMemoryParamRetval">,
+      DefaultFalse,
+      PosFlag<SetTrue, [CC1Option], "Enable">, NegFlag<SetFalse, [], "Disable">,
+      BothFlags<[], " detection of uninitialized parameters and return values">>,
+    Group<f_clang_Group>;
 // Note: This flag was introduced when it was necessary to distinguish between
 //       ABI for correct codegen.  This is no longer needed, but the flag is
 //       not removed since targeting either ABI will behave the same.
diff --git a/clang/include/clang/Driver/SanitizerArgs.h b/clang/include/clang/Driver/SanitizerArgs.h
--- a/clang/include/clang/Driver/SanitizerArgs.h
+++ b/clang/include/clang/Driver/SanitizerArgs.h
@@ -33,6 +33,7 @@
   int CoverageFeatures = 0;
   int MsanTrackOrigins = 0;
   bool MsanUseAfterDtor = true;
+  bool MsanParamRetval = false;
   bool CfiCrossDso = false;
   bool CfiICallGeneralizePointers = false;
   bool CfiCanonicalJumpTables = false;
diff --git a/clang/lib/Driver/SanitizerArgs.cpp b/clang/lib/Driver/SanitizerArgs.cpp
--- a/clang/lib/Driver/SanitizerArgs.cpp
+++ b/clang/lib/Driver/SanitizerArgs.cpp
@@ -641,10 +641,14 @@
         Args.hasFlag(options::OPT_fsanitize_memory_use_after_dtor,
                      options::OPT_fno_sanitize_memory_use_after_dtor,
                      MsanUseAfterDtor);
+    MsanParamRetval = Args.hasFlag(
+        options::OPT_fsanitize_memory_param_retval,
+        options::OPT_fno_sanitize_memory_param_retval, MsanParamRetval);
     NeedPIE |= !(TC.getTriple().isOSLinux() &&
                  TC.getTriple().getArch() == llvm::Triple::x86_64);
   } else {
     MsanUseAfterDtor = false;
+    MsanParamRetval = false;
   }
 
   if (AllAddedKinds & SanitizerKind::Thread) {
@@ -1096,6 +1100,9 @@
   if (MsanUseAfterDtor)
     CmdArgs.push_back("-fsanitize-memory-use-after-dtor");
 
+  if (MsanParamRetval)
+    CmdArgs.push_back("-fsanitize-memory-param-retval");
+
   // FIXME: Pass these parameters as function attributes, not as -llvm flags.
   if (!TsanMemoryAccess) {
     CmdArgs.push_back("-mllvm");
diff --git a/clang/test/Driver/fsanitize-memory-param-retval.c b/clang/test/Driver/fsanitize-memory-param-retval.c
new file mode 100644
--- /dev/null
+++ b/clang/test/Driver/fsanitize-memory-param-retval.c
@@ -0,0 +1,12 @@
+// RUN: %clang -target i386-gnu-linux %s -fsanitize=memory -fsanitize-memory-param-retval -c -### 2>&1 | FileCheck %s
+// RUN: %clang -target x86_64-linux-gnu %s -fsanitize=memory -fsanitize-memory-param-retval -c -### 2>&1 | FileCheck %s
+// RUN: %clang -target aarch64-linux-gnu %s -fsanitize=memory -fsanitize-memory-param-retval -c -### 2>&1 | FileCheck %s
+// RUN: %clang -target riscv32-linux-gnu %s -fsanitize=memory -fsanitize-memory-param-retval -c -### 2>&1 | FileCheck %s
+// RUN: %clang -target riscv64-linux-gnu %s -fsanitize=memory -fsanitize-memory-param-retval -c -### 2>&1 | FileCheck %s
+// CHECK: "-fsanitize-memory-param-retval"
+
+// RUN: %clang -target aarch64-linux-gnu -fsyntax-only %s -fsanitize=memory -fsanitize-memory-param-retval -c -### 2>&1 | FileCheck --check-prefix=11 %s
+// 11: "-fsanitize-memory-param-retval"
+
+// RUN: not %clang -target x86_64-linux-gnu -fsyntax-only %s -fsanitize=memory -fsanitize-memory-param-retval=1 2>&1 | FileCheck --check-prefix=EXCESS %s
+// EXCESS: error: unknown argument: '-fsanitize-memory-param-retval=