diff --git a/clang/lib/Basic/Targets/AArch64.h b/clang/lib/Basic/Targets/AArch64.h
--- a/clang/lib/Basic/Targets/AArch64.h
+++ b/clang/lib/Basic/Targets/AArch64.h
@@ -53,6 +53,7 @@
   bool HasMatmulFP32;
   bool HasLSE;
   bool HasFlagM;
+  bool HasMOPS;
 
   llvm::AArch64::ArchKind ArchKind;
 
diff --git a/clang/lib/Basic/Targets/AArch64.cpp b/clang/lib/Basic/Targets/AArch64.cpp
--- a/clang/lib/Basic/Targets/AArch64.cpp
+++ b/clang/lib/Basic/Targets/AArch64.cpp
@@ -435,6 +435,9 @@
   if (HasRandGen)
     Builder.defineMacro("__ARM_FEATURE_RNG", "1");
 
+  if (HasMOPS)
+    Builder.defineMacro("__ARM_FEATURE_MOPS", "1");
+
   switch (ArchKind) {
   default:
     break;
@@ -660,6 +663,17 @@
       HasFlagM = true;
   }
 
+  HasMOPS |= ArchKind == llvm::AArch64::ArchKind::ARMV8_8A ||
+             ArchKind == llvm::AArch64::ArchKind::ARMV9_3A;
+
+  // Check features that are manually disabled by command line options.
+  // This needs to be checked after architecture-related features are handled,
+  // making sure they are properly disabled when required.
+  for (const auto &Feature : Features) {
+    if (Feature == "-mops")
+      HasMOPS = false;
+  }
+
   setDataLayout();
 
   return true;
diff --git a/clang/test/Preprocessor/aarch64-target-features.c b/clang/test/Preprocessor/aarch64-target-features.c
--- a/clang/test/Preprocessor/aarch64-target-features.c
+++ b/clang/test/Preprocessor/aarch64-target-features.c
@@ -517,3 +517,13 @@
 // RUN: %clang -target aarch64-none-linux-gnu -march=armv8.1-a -x c -E -dM %s -o - | FileCheck --check-prefix=CHECK-LSE %s
 // RUN: %clang -target arm64-none-linux-gnu -march=armv8.1-a -x c -E -dM %s -o - | FileCheck --check-prefix=CHECK-LSE %s
 // CHECK-LSE: __ARM_FEATURE_ATOMICS 1
+
+// ================== Check Armv8.8-A/Armv9.3-A memcpy and memset acceleration instructions (MOPS)
+// RUN: %clang -target aarch64-arm-none-eabi -march=armv8-a+mops -x c -E -dM %s -o - | FileCheck --check-prefix=CHECK-MOPS %s
+// RUN: %clang -target aarch64-arm-none-eabi -march=armv8.8-a -x c -E -dM %s -o - | FileCheck --check-prefix=CHECK-MOPS %s
+// RUN: %clang -target aarch64-arm-none-eabi -march=armv8.8-a+nomops -x c -E -dM %s -o - | FileCheck --check-prefix=CHECK-NOMOPS %s
+// RUN: %clang -target aarch64-arm-none-eabi -march=armv9-a+mops -x c -E -dM %s -o - | FileCheck --check-prefix=CHECK-MOPS %s
+// RUN: %clang -target aarch64-arm-none-eabi -march=armv9.3-a -x c -E -dM %s -o - | FileCheck --check-prefix=CHECK-MOPS %s
+// RUN: %clang -target aarch64-arm-none-eabi -march=armv9.3-a+nomops -x c -E -dM %s -o - | FileCheck --check-prefix=CHECK-NOMOPS %s
+// CHECK-MOPS: __ARM_FEATURE_MOPS 1
+// CHECK-NOMOPS-NOT: __ARM_FEATURE_MOPS 1
diff --git a/llvm/include/llvm/Support/AArch64TargetParser.h b/llvm/include/llvm/Support/AArch64TargetParser.h
--- a/llvm/include/llvm/Support/AArch64TargetParser.h
+++ b/llvm/include/llvm/Support/AArch64TargetParser.h
@@ -69,6 +69,7 @@
   AEK_SME =         1ULL << 37,
   AEK_SMEF64 =      1ULL << 38,
   AEK_SMEI64 =      1ULL << 39,
+  AEK_MOPS =        1ULL << 40,
 };
 
 enum class ArchKind {