diff --git a/llvm/lib/CodeGen/SelectionDAG/DAGCombiner.cpp b/llvm/lib/CodeGen/SelectionDAG/DAGCombiner.cpp
--- a/llvm/lib/CodeGen/SelectionDAG/DAGCombiner.cpp
+++ b/llvm/lib/CodeGen/SelectionDAG/DAGCombiner.cpp
@@ -4436,7 +4436,7 @@
   if (DAG.isKnownNeverZero(N1) && !TLI.isIntDivCheap(VT, Attr)) {
     SDValue OptimizedDiv =
         isSigned ? visitSDIVLike(N0, N1, N) : visitUDIVLike(N0, N1, N);
-    if (OptimizedDiv.getNode()) {
+    if (OptimizedDiv.getNode() && OptimizedDiv.getNode() != N) {
       // If the equivalent Div node also exists, update its users.
       unsigned DivOpcode = isSigned ? ISD::SDIV : ISD::UDIV;
       if (SDNode *DivNode = DAG.getNodeIfExists(DivOpcode, N->getVTList(),
diff --git a/llvm/test/CodeGen/AArch64/sve-srem-combine-loop.ll b/llvm/test/CodeGen/AArch64/sve-srem-combine-loop.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/AArch64/sve-srem-combine-loop.ll
@@ -0,0 +1,19 @@
+; NOTE: Assertions have been autogenerated by utils/update_llc_test_checks.py
+; RUN: llc < %s | FileCheck %s
+
+target triple = "aarch64-unknown-linux-gnu"
+
+define <vscale x 4 x i32> @srem_combine_loop(<vscale x 4 x i32> %a) #0 {
+; CHECK-LABEL: srem_combine_loop:
+; CHECK:       // %bb.0:
+; CHECK-NEXT:    mov z1.d, z0.d
+; CHECK-NEXT:    ptrue p0.s
+; CHECK-NEXT:    asrd z1.s, p0/m, z1.s, #1
+; CHECK-NEXT:    mov z2.s, #2 // =0x2
+; CHECK-NEXT:    mls z0.s, p0/m, z1.s, z2.s
+; CHECK-NEXT:    ret
+  %rem = srem <vscale x 4 x i32> %a, shufflevector (<vscale x 4 x i32> insertelement (<vscale x 4 x i32> poison, i32 2, i32 0), <vscale x 4 x i32> poison, <vscale x 4 x i32> zeroinitializer)
+  ret <vscale x 4 x i32> %rem
+}
+
+attributes #0 = { "target-features"="+sve" }