diff --git a/llvm/include/llvm/Transforms/Instrumentation/InstrProfiling.h b/llvm/include/llvm/Transforms/Instrumentation/InstrProfiling.h
--- a/llvm/include/llvm/Transforms/Instrumentation/InstrProfiling.h
+++ b/llvm/include/llvm/Transforms/Instrumentation/InstrProfiling.h
@@ -56,6 +56,9 @@
     }
   };
   DenseMap<GlobalVariable *, PerFunctionProfileData> ProfileDataMap;
+  /// If runtime relocation is enabled, this maps functions to the load
+  /// instruction that produces the profile relocation bias.
+  DenseMap<const Function *, LoadInst *> FunctionToProfileBiasMap;
   std::vector<GlobalValue *> CompilerUsedVars;
   std::vector<GlobalValue *> UsedVars;
   std::vector<GlobalVariable *> ReferencedNames;
diff --git a/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp b/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
--- a/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
+++ b/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
@@ -703,10 +703,9 @@
 
   Type *Int64Ty = Type::getInt64Ty(M->getContext());
   Function *Fn = I->getParent()->getParent();
-  Instruction &EntryI = Fn->getEntryBlock().front();
-  LoadInst *LI = dyn_cast<LoadInst>(&EntryI);
-  if (!LI) {
-    IRBuilder<> EntryBuilder(&EntryI);
+  LoadInst *&BiasLI = FunctionToProfileBiasMap[Fn];
+  if (!BiasLI) {
+    IRBuilder<> EntryBuilder(&Fn->getEntryBlock().front());
     auto *Bias = M->getGlobalVariable(getInstrProfCounterBiasVarName());
     if (!Bias) {
       // Compiler must define this variable when runtime counter relocation
@@ -723,9 +722,9 @@
       if (TT.supportsCOMDAT())
         Bias->setComdat(M->getOrInsertComdat(Bias->getName()));
     }
-    LI = EntryBuilder.CreateLoad(Int64Ty, Bias);
+    BiasLI = EntryBuilder.CreateLoad(Int64Ty, Bias);
   }
-  auto *Add = Builder.CreateAdd(Builder.CreatePtrToInt(Addr, Int64Ty), LI);
+  auto *Add = Builder.CreateAdd(Builder.CreatePtrToInt(Addr, Int64Ty), BiasLI);
   return Builder.CreateIntToPtr(Add, Addr->getType());
 }